# US 11,111,213 B2 · Method for producing methionine

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- Number: US 11,111,213 B2
- Document ID: US11111213B2
- Status: Granted
- Kind: B2
- Application number: 16/608,002
- Filed: 2018-04-27
- Published: 2021-04-08
- Granted: 2021-09-07
- Earliest claimed: 2017-04-27
- Assignees: Sumitomo Chemical Company, Limited
- Applicants: Sumitomo Chemical Company, Limited
- Inventors: Yoshitaka Satoh; Norihito Omoto; Yoshiyuki Koizumi; Naoya Yamashiro; Ryousuke Katagami
- Web page: https://patentgrep.com/patent/US11111213B2

## CPC

- C07C 319/28: Separation; Purification
- C07C 319/20: by reactions not involving the formation of sulfide groups
- C07C 323/58: with amino groups bound to the carbon skeleton
- C07C: ACYCLIC OR CARBOCYCLIC COMPOUNDS

## Abstract

The present provides a method for producing methionine which is characterized by a crystallization step in which carbon dioxide is introduced into a reaction solution containing an alkali salt of methionine which is obtained by hydrolyzing 5-[2-(methylthio)ethyl] imidazoline-2,4-dione in the presence of an alkali compound, thereby precipitating the methionine, and further comprises a step of adding waste methionine to the reaction solution. The method of production of the present invention can improve a yield in the production of methionine.

## Claims

### Claim 1

A method for producing methionine comprising
a) a crystallization step in which carbon dioxide is introduced into a reaction solution containing an alkali metal salt of methionine, which is obtained by hydrolyzing 5-[2-(methylthio)ethyl] imidazolidine-2,4-dione in the presence of an alkali compound selected from the group consisting of potassium hydroxide, sodium hydroxide, potassium carbonate, and potassium hydrogencarbonate, to precipitate methionine,
b) a step of subjecting the reaction solution containing precipitated methionine resulting in the crystallization step to a solid-liquid separation to obtain methionine and mother liquor,
c) a step of recovering methionine from the mother liquor by filtration,
d) a step of drying the methionine obtained by step c) to obtain dried methionine, wherein the drying step also produces an exhaust,
e) a step of sieving the dried methionine to obtain sieved methionine,
f) a step of packaging the sieved methionine powders to obtain a packaged methionine product, and
g) a step of transporting methionine between each of the steps c) to f),
wherein the method comprises a step of adding waste methionine to the reaction solution, wherein the waste methionine supplied to the hydrolysis reaction solution includes
recovered methionine in step c), and
at least one recovered methionine selected from the group consisting of
methionine discharged out of the system due to exhaust in the drying step,
fine powdered methionine passed through a sieve mesh in the sieving step,
methionine that is soared when filling a container with methionine in the product packaging step, and
methionine lost during any of the transporting steps.

### Claim 2 (depends on 1)

The method for producing methionine according to claim 1, wherein the step of adding the waste methionine to the reaction solution is conducted by dissolving the waste methionine in the reaction solution.

### Claim 3 (depends on 1)

The method for producing methionine according to claim 1, wherein the step of adding the waste methionine to the reaction solution is conducted by dissolving the waste methionine in water, and then adding the dissolved methionine to the reaction solution.

### Claim 4 (depends on 1)

The method for producing methionine according to claim 1, wherein step c) further comprises a washing step in which the methionine obtained by the solid-liquid separation is washed, and further comprises adding the washing liquid separated in the washing step to the reaction solution.