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US 11,111,210 B2Granted
Phenyl cyclohexanone derivatives and methods of making and using them
AssigneeSpirify Pharma Inc.
InventorIrving W. Wainer
Life of this patent
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Abstract
Phenyl cyclohexanone based active agents, pharmaceutical preparations containing such active agents, methods of modifying cellular activity by contacting cells with such active agents, and methods of treating various conditions by administering such active agents to a patient are described.
Claims20
A phenyl cyclohexanone compound of Formula I or pharmaceutically acceptable salt thereof:
- R1 is —NH2 or —OH;
- R2 is,
- where Rx is Cl, Br, —OCH3, or NH2;
- R3 is —OH, —OCH3, —NH2, —CN, —SO2—NH2,
- R4 is —OH, or —OCH3;
- and
- R5 is —OH, —NH2, or ═O.
4 more elements
A phenyl cyclohexanone compound selected from:
A phenyl cyclohexanone compound or a pharmaceutically acceptable salt of the formula:
- R1 is —NH2 or OH;
- R2 is,
- where Rx is Cl, Br, —OCH3, or —NH2;
- R3 is —OH, —CN, —SO2—NH2
- R4 is —H, —OH, or —OCH3, and
- R5 is —OH, —NH2, or ═O.
3 more elements
Dependencies are inferred from the claim text.