# US 11,110,292 B2 · Balanced cone excitation for controlling refractive error and ocular growth to inhibit development of myopia > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,110,292 B2 - Document ID: US11110292B2 - Status: Granted - Kind: B2 - Application number: 16/353,107 - Filed: 2019-03-14 - Published: 2019-09-19 - Granted: 2021-09-07 - Earliest claimed: 2018-03-19 - Assignees: New England College of Optometry - Applicants: Frances Joan Rucker; Hannah Yoon; Christopher Patrick Taylor - Inventors: Frances Joan Rucker; Hannah Yoon; Christopher Patrick Taylor - Web page: https://patentgrep.com/patent/US11110292B2 ## CPC - A61N 5/0613: {Apparatus adapted for a specific treatment} - A61N 5/0622: {Optical stimulation for exciting neural tissue} - A61N 2005/0628: {including a radiation sensor} - A61N 2005/0642: {Irradiating part of the body at a certain distance} - A61N 2005/0648: {the light being directed to the eyes} - A61N 2005/0651: {Diodes} - A61N 2005/0652: {Arrays of diodes} - A61N 2005/0663: {Coloured light} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) ## Abstract A myopia-inhibiting treatment device produces a therapeutic light that includes components of different wavelengths in a ratio of luminosities that creates a predetermined L-cone to S-cone excitation profile that slows ocular growth, thereby mitigating development of myopia. The components comprise blue light, green light, and red light. Therapeutic light may cause an L-cone to S-cone excitation ratio in a range between 1.38 and 0.05. In some implementations the therapeutic light causes a L-cone to S-cone excitation ratio of 0.74. In some implementations the luminosity of the combined light components is greater than 700 lux. ## Claims ### Claim 1 An apparatus comprising: a computer; a light source that produces a therapeutic light in response to control signals from the computer; and a spectroradiometer that measures spectral characteristics of components of the therapeutic light and provides an indication of radiance of the spectral characteristics of the components of the therapeutic light to the computer; wherein the computer generates the control signals based on the radiance and spectral characteristics of the therapeutic light such that the therapeutic light comprises components of different wavelengths in a predetermined ratio of radiance calculated to create a balanced L-cone to S-cone excitation profile that slows ocular growth thereby mitigating development of myopia, and wherein the predetermined ratio of component radiances of the therapeutic light is calculated to create an L-cone to S-cone excitation ratio in a range between 0.74 and 1.38. ### Claim 2 (depends on 1) The apparatus of claim 1 wherein the components comprise blue light, green light, and red light. ### Claim 3 (depends on 1) The apparatus of claim 1 further comprising a lux meter that measures illumination of the combined components and provides an indication of the illumination of the combined light components to the computer, wherein the illumination of the combined components is set by the computer to be greater than 700 lux. ### Claim 4 (depends on 1) The apparatus of claim 1 wherein the ratio of radiances of the therapeutic light is calculated to create a L-cone to S-cone excitation ratio of 0.74. ### Claim 5 (depends on 1) The apparatus of claim 1 wherein the computer calculates the balanced L-cone to S-cone excitation profile based on a radiance profile and the spectral characteristics of the therapeutic light provided by the spectroradiometer, and cone sensitivities. ### Claim 6 (depends on 1) The apparatus of claim 1 wherein the computer calculates component radiances corresponding to the predetermined L-cone to S-cone excitation profile that slows ocular growth. ### Claim 7 (depends on 6) The apparatus of claim 6 wherein the computer controls the light source to generate different component radiances for different lighting environments. ### Claim 8 (depends on 7) The apparatus of claim 7 wherein the computer controls the light source to temporally modulate the component radiances. ### Claim 9 A method comprising: producing a therapeutic light with a computer-controlled light source that uses feedback to provide radiance and spectral characteristics of components of different wavelengths of the therapeutic light, comprising: calculating radiances of the components and adjusting intensity of the different wavelengths to produce a predetermined balanced L-cone to S-cone excitation profile that slows ocular growth, simulating a signal that arises from longitudinal chromatic aberration, wherein the components comprise blue light, green light, and red light, that are adjusted in intensity to cause an L-cone to S-cone excitation ratio in a range between 0.74 and 1.38 and which are modulated to enhance therapeutic effect; and generating control signals to cause the light source to generate the therapeutic light with the calculated radiances; and using the therapeutic light to mitigate development of myopia. ### Claim 10 (depends on 9) The method of claim 9 comprising modulating illumination of the combined light components to greater than 700 lux. ### Claim 11 (depends on 9) The method of claim 9 wherein the components comprise blue light, green light, and red light, and comprising modulating the components to cause an L-cone to S-cone excitation ratio of 0.74. ### Claim 12 (depends on 9) The method of claim 9 comprising using a computer to calculate component radiances corresponding to the predetermined L-cone to S-cone excitation profile that slows ocular growth. ### Claim 13 A non-transitory computer-readable storage medium comprising: calculation logic that calculates component radiances corresponding to a predetermined balanced L-cone to M-cone to S-cone excitation profile that slows ocular growth, simulating a signal that arises from longitudinal chromatic aberration; and control logic that modulates components of a light source to cause an L-cone to M-cone to S-cone excitation ratio in a range between 0.74 and 1.38 using feedback that controls the radiance of the components of the light source. ### Claim 14 (depends on 13) The non-transitory computer-readable storage medium of claim 13 wherein the components comprise blue light, green light, and red light, and wherein the control logic modulates the components to cause an L-cone to S-cone excitation ratio of 0.74. ### Claim 15 (depends on 14) The non-transitory computer-readable storage medium of claim 14 comprising power-setting logic that sets illumination of the combined light components to greater than 700 lux.