Brain neurostimulator electrode fitting
AssigneeClosed Loop Medical Pty Ltd
InventorsJohn Louis Parker, Gerrit Eduard Gmel
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Abstract
Fitting a brain neurostimulator electrode array comprises positioning at least a first electrode in a desired target structure in a first cerebral hemisphere, and positioning at least a second electrode in a corresponding target structure in a contralateral cerebral hemisphere. Electrical stimuli are applied from the first electrode to the desired target structure. Neural responses observed at the second electrode in response to the electrical stimuli are recorded. The fitting of at least one of the first electrode and second electrode is assessed by reference to the recorded neural responses.
Claims21
A method of fitting a brain neurostimulator electrode array, the method comprising:
- positioning at least a first electrode in a desired target structure in a first ipsilateral cerebral hemisphere;
- positioning at least a second electrode in a corresponding target structure in a second contralateral cerebral hemisphere;
- applying an ipsilateral electrical stimuli from the first electrode to the desired target structure in the first ipsilateral cerebral hemisphere;
- recording evoked compound action potentials observed in the second contralateral cerebral hemisphere at the second electrode in response to the electrical stimuli;
- processing evoked compound action potentials observed at the second electrode so as to determine at least one of a presence, an amplitude, a morphology, and a latency of the evoked compound action potentials observed at the second electrode;
- and
- assessing the fitting of at least one of the first electrode and second electrode by reference to the recorded evoked compound action potential.
A brain neurostimulator device comprising:
- at least a first electrode configured to be positioned in a desired target structure in a first ipsilateral cerebral hemisphere;
- at least a second electrode configured to be positioned in a corresponding target structure in a second contralateral cerebral hemisphere;
- a pulse generator configured to apply an ipsilateral electrical stimuli from the first electrode to the desired target structure in the first ipsilateral cerebral hemisphere;
- measurement circuitry configured to record evoked compound action potentials observed in the second contralateral cerebral hemisphere at the second electrode in response to the electrical stimuli;
- and
- a processor configured to process the evoked compound action potentials observed at the second electrode so as to determine at least one of a presence, an amplitude, a morphology, and a latency of the evoked compound action potentials observed at the second electrode, and further configured to assess the fitting of at least one of the first electrode and second electrode by reference to the recorded evoked compound action potentials.
A non-transitory computer readable medium for fitting a brain neurostimulator electrode array, the computer readable medium comprising computer program code means for applying electrical stimuli from a first electrode positioned in a desired target structure in a first ipsilateral cerebral hemisphere, to the desired target structure;
- computer program code means for recording evoked compound action potentials observed at a second electrode in a corresponding target structure in a second contralateral cerebral hemisphere in response to the electrical stimuli;
- computer program code means for processing the evoked compound action potentials observed at the second electrode so as to determine at least one of a presence, an amplitude, a morphology, and a latency of the evoked compound action potentials observed at the second electrode;
- and
- computer program code means for assessing the fitting of at least one of the first electrode and second electrode by reference to the recorded evoked compound action potentials.
Dependencies are inferred from the claim text.