Systems and methods for applying media to skin

A device for treatment of a subject's skin or lips, comprising:

• an applicator body having a distal applicator tip;
• the applicator tip including an inflow path channel and an outflow path;
• a liquid media source in communication with the inflow path;
• a negative pressure source in communication the outflow path configured to pull a negative pressure in the applicator body;
• a collector in the outflow path adapted to capture liquid media from a flow therein;
• and
• a rolling member rotatably exposed at the applicator tip, the rolling member comprising a plurality of surface discontinuities in a surface of the rolling member such that the plurality of surface discontinuities permit transient application of the negative pressure to the subject's skin or lips.

A method for treating a targeted skin of a subject, comprising:

• providing an applicator carrying a motor-driven pump assembly for providing negative pressure through a distal tip of the applicator;
• applying a treatment media to the targeted skin;
• contacting the targeted skin with the distal tip of the applicator to manipulate the targeted skin;
• and
• drawing negative pressure in the applicator while moving the distal tip in contact with the targeted skin such that moving the distal tip causes transient application of negative pressure at a plurality of locations on the targeted skin and on a corresponding subsurface tissue, which enhances penetration of the treatment media into the targeted skin.

A method for treating hair loss in a targeted tissue of a subject, the method comprising:

• applying a treatment media configured to aid in hair growth to targeted tissue of the subject;
• contacting the targeted tissue with an applicator having a rolling member;
• rolling the rolling member on the targeted tissue on the targeted tissue with the applicator to enhance penetration of the treatment media therein by at least one of compressing, stretching, tensioning, exfoliating and piercing a tissue surface with surface features of the applicator;
• drawing a negative pressure through a flow path around the rolling member when in contact with the targeted tissue to transiently apply the negative pressure in a subsurface tissue to enhance penetration of the treatment media into the targeted tissue.

A method for treating hair loss in a targeted tissue of a subject, the method comprising:

• applying a treatment media configured to aid in hair growth to targeted tissue of the subject;
• contacting the targeted tissue with an applicator having a rolling member;
• and
• moving the applicator over the targeted tissue by rolling the rolling member on the targeted tissue to exfoliate the targeted tissue with a surface feature of the rolling member to enhance penetration of the treatment media in the targeted tissue;
• drawing a negative pressure about the applicator when in contact with the targeted tissue to transiently apply the negative pressure in a subsurface tissue to enhance penetration of the treatment media into the targeted tissue.

A method for treating a subject's skin, comprising:

• providing an applicator carries a motor-driven pump assembly for providing negative pressure in the applicator;
• applying treatment media to a targeted skin of a subject;
• contacting the targeted skin with an applicator to manipulate the targeted skin;
• and
• drawing negative pressure about the applicator while moving the applicator in contact with the targeted tissue to transiently cause negative pressure in a subsurface tissue to enhance penetration of the treatment media into the targeted skin and results in outflows around or through a surface of a rolling member carried at a distal end of the applicator.