# US 11,110,208 B2 · Implant, preferably for the treatment of an acetabular defect

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- Number: US 11,110,208 B2
- Document ID: US11110208B2
- Status: Granted
- Kind: B2
- Application number: 16/323,078
- Filed: 2017-08-01
- Published: 2019-06-13
- Granted: 2021-09-07
- Earliest claimed: 2016-08-02
- Assignees: Aesculap AG
- Applicants: Aesculap AG
- Inventors: Silke Koenig
- Web page: https://patentgrep.com/patent/US11110208B2

## CPC

- A61L 27/58: Materials at least partially resorbable by the body
- A61L 27/047: {Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06}
- A61L 27/18: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- A61L 27/24: Collagen
- A61L 27/3604: {characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel}
- A61L 27/3625: {Vascular tissue, e.g. heart valves}
- A61L 27/54: Biologically active materials, e.g. therapeutic substances {(A61L27/227 takes precedence)}
- A61L 27/56: Porous materials, {e.g. foams or sponges}
- A61L 2300/406: Antibiotics
- A61L 2430/02: for reconstruction of bones; weight-bearing implants
- A61L 2430/24: for joint reconstruction
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)

## Abstract

An implant, preferably for treating and/or reconstructing, in particular lining and/or sealing and/or relining and/or at least partially filling an acetabular defect, having at least one flat structure which contains a material that is at least partially decomposable or resorbable in vivo. The invention further relates to a surgical kit and the use of an unfinished flat structure for producing an implant.

## Claims

### Claim 1

An implant for use in treating an acetabular defect, having at least one flat structure which contains a material that is at least partially decomposable or resorbable in vivo, wherein the implant has two flat structures, wherein each flat structure has a central area and three elongated functional areas that extend out from the central area, and wherein the flat structures are arranged one above the other in such a way that the elongated functional areas of one of the two flat structures are arranged offset to the elongated functional areas of the other of the two flat structures.

### Claim 2 (depends on 1)

The implant of claim 1, wherein the material has a randomized fiber structure.

### Claim 3 (depends on 1)

The implant of claim 1, wherein the material is free of non-collagenous components.

### Claim 4 (depends on 1)

The implant of claim 1, characterized in that the material is a protein.

### Claim 5 (depends on 4)

The implant of claim 4, characterized in that the protein is selected from the group composed of collagen, gelatin, elastin, reticulin, fibrin, fibronectin, laminin, albumin and mixtures of at least two of the aforementioned proteins.

### Claim 6 (depends on 4)

The implant of claim 4, characterized in that the protein is collagen.

### Claim 7 (depends on 1)

The implant of claim 1, wherein the material is a xenogeneic tissue.

### Claim 8 (depends on 7)

The implant of claim 7, wherein the xenogeneic tissue is bovine tissue.

### Claim 9 (depends on 7)

The implant of claim 7, wherein the tissue is pericardium.

### Claim 10 (depends on 9)

The implant of claim 9, wherein the pericardium is bovine pericardium.

### Claim 11 (depends on 1)

The implant of claim 1, characterized in that the material is a synthetic polymer selected from the group composed of polyglycolide, polylactide, poly-ε-caprolactone, polytrimethylene carbonate, poly-3-hydroxybutyrate, poly-4-hydroxybutyrate, poly-p-dioxanone, copolymers thereof and blends of at least two of the aforementioned polymers.

### Claim 12 (depends on 1)

The implant of claim 1, wherein the at least one flat structure is in freeze-dried form.

### Claim 13 (depends on 1)

The implant of claim 1, characterized in that the material is a metal.

### Claim 14 (depends on 1)

The implant of claim 1, wherein the at least one flat structure has penetrating holes, perforations or slits.

### Claim 15 (depends on 1)

The implant of claim 1, wherein the at least one flat structure has a central area and elongated functional areas that extend out from the central area.

### Claim 16 (depends on 15)

The implant of claim 15, wherein the elongated functional areas are strip-shaped functional areas.

### Claim 17 (depends on 1)

The implant of claim 1, wherein the implant has a plurality of flat structures, wherein the flat structures are arranged one above the other and are connected to one another at the edges.

### Claim 18 (depends on 17)

The implant of claim 17, wherein adjacent flat structures enclose a cavity.

### Claim 19 (depends on 17)

The implant of claim 17, wherein the flat structures are sewn or adhesively bonded to one another at the edges.

### Claim 20 (depends on 1)

The implant of claim 1, wherein the implant further comprises an additive.

### Claim 21 (depends on 20)

The implant of claim 20, wherein the additive is located between two flat structures that are arranged one above the other and are connected to each other.

### Claim 22 (depends on 20)

The implant of claim 20, wherein the additive is located between central areas of flat structures that are arranged one above the other and are connected to each other.

### Claim 23 (depends on 20)

The implant of claim 20, wherein the additive is located between functional areas of flat structures that are arranged one above the other and are connected to each other.

### Claim 24 (depends on 20)

The implant of claim 20, wherein the additive is an osteoconductive additive.

### Claim 25 (depends on 24)

The implant of claim 24, wherein the osteoconductive additive is calcium sulfate, hydroxyapatite, calcium phosphate, a-tricalcium phosphate, collagen, a collagen hydroxyapatite mixture, silicon hydroxyapatite, magnesium hydroxyapatite, bioactive glass, bone chips, or a mixture of at least two of the aforementioned additives.

### Claim 26 (depends on 1)

The implant of claim 1, wherein the implant further comprises a textile, in particular knitted, mesh.

### Claim 27 (depends on 26)

The implant of claim 26, wherein the textile mesh is a knitted mesh.

### Claim 28 (depends on 1)

A surgical kit comprising an implant as claimed in claim 1 and at least one component selected from the group composed of bone filling material, textile mesh, bone adhesive, endoprosthesis, supporting shell, spacer implant and fastening element.
