Esculentin 1a derivatives and uses thereof
AssigneesUniversity of Houston System, Universita' Degli Studi Di Roma “La Sapienza”
InventorsAlison McDermott, Maria Luisa Mangoni
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Abstract
Provided herein are synthetic antibacterial peptides that have a sequence at least 80% identical to a sequence shown in SEQ ID NO: 2 or the diastereomer thereof with a sequence shown in SEQ ID NO: 3 or pharmaceutical compositions thereof. Also provided are methods for stimulating wound healing via the synthetic antibacterial peptides and for forming an antimicrobial coating on contact lenses. In addition a device is provided that has a surface with a coating of the synthetic antibacterial peptides.
Claims8
A method for stimulating wound healing, comprising the step of contacting a wound with an antimicrobial component comprising an antibacterial peptide with a sequence at least 80% identical to the sequence of SEQ ID NO:
- 2 or a diastereomer thereof with a sequence at least 80% identical to the sequence of SEQ ID NO:
- 3.
Dependencies are inferred from the claim text.