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US 11,110,092 B2Granted
Methods of treating hematologic cancers
AssigneeBioCryst Pharmaceuticals, Inc.
InventorsShanta Bantia, Philip Breitfeld, Yarlagadda S Babu
Life of this patent
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Abstract
The present application relates to treatment of hematologic cancers, which treatments can include, e.g., administration of a purine nucleoside phosphorylase (PNP) inhibitor, an alkylating agent and/or an anti-CD20 agent, and related compositions and kits.
Claims6
A method of treating a hematologic cancer in a subject comprising the steps of:
- a. administering to the subject an effective amount Forodesine;
- and
- b. administering to the subject an effective amount of an alkylating agent, wherein the administration of Forodesine and the alkylating agent results in a synergistic effect, wherein the alkylating agent is Bendamustine and the hematologic cancer is resistant to Bendamustine and Fludarabine.
Dependencies are inferred from the claim text.