# US 11,109,615 B2 · Vitamin A composition

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- Number: US 11,109,615 B2
- Document ID: US11109615B2
- Status: Granted
- Kind: B2
- Application number: 15/548,163
- Filed: 2016-02-10
- Published: 2018-01-11
- Granted: 2021-09-07
- Earliest claimed: 2015-02-11
- Assignees: Societe des Produits Nestle S.A.
- Applicants: Nestec S.A.
- Inventors: Laurent Sagalowicz; Charlotte Gancel; Cyril Moccand; Isabelle Martiel
- Web page: https://patentgrep.com/patent/US11109615B2

## CPC

- A23L 33/155: Vitamins A or D
- A23L 27/20: Synthetic spices, flavouring agents or condiments
- A23L 29/10: containing emulsifiers
- A23L 33/105: Plant extracts, their artificial duplicates or their derivatives
- A61K 9/107: Emulsions {; Emulsion preconcentrates; Micelles (composition of emulsions A61K47/00)}
- A61K 31/07: Retinol compounds, e.g. vitamin A (retinoic acids A61K31/203)
- A61K 47/14: Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A61K 9/1075: {Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers (A61K9/0026 takes precedence)}
- A61K 9/1274: Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases or cochleates; Sponge phases
- A61K 47/22: Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A61K 47/24: containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

The present invention relates to a composition comprising triglycerides, surfactant, self-assembled structures and vitamin A or provitamin A. Further aspects of the invention are a food product, the use of a composition comprising triglycerides, surfactant and self-assembled structures to stabilize vitamin A or provitamin A and a process for preparing a stabilized vitamin A or provitamin A composition.

## Claims

### Claim 1

A process for preparing a stabilized vitamin A or provitamin A composition, the process comprising:
providing triglycerides, lecithin, and at least one liquid compound selected from the group consisting of vitamin A and provitamin A; and
mixing the triglycerides, the lecithin and the at least one compound to form the stabilized vitamin A or provitamin A composition,
wherein the stabilized vitamin A or provitamin A composition consists of the triglycerides, the lecithin, the at least one compound, and water;
the triglycerides are at least 50 wt. % of the total weight of the stabilized vitamin A or provitamin A composition;
the lecithin is 0.1-30 wt. % based on the amount of the triglycerides; and
the stabilized vitamin A or provitamin A composition has a water content between 0.001 wt % and 4 wt. % of the total weight of the stabilized vitamin A or provitamin A composition.

### Claim 2 (depends on 1)

The process according to claim 1, wherein at least a portion of the lecithin forms self-assembled structures having a reversed micellar cubic structure.

### Claim 3 (depends on 1)

The process according to claim 1, wherein at least part of the at least one compound is dissolved in the triglycerides.

### Claim 4 (depends on 1)

The process according to claim 1, wherein the process further comprises adding and mixing an antioxidant to the stabilized vitamin A or provitamin A composition.

### Claim 5 (depends on 4)

The process according to claim 4, wherein the antioxidant is selected from the group consisting of rosemary extract, green tea extract, a butylated phenol and combinations thereof.

### Claim 6 (depends on 1)

The process according to claim 1, wherein the stabilized vitamin A or provitamin A composition has a water activity greater than 0.3.

### Claim 7 (depends on 1)

The process according to claim 1, wherein the surfactant is 0.5-6 wt. % of the stabilized vitamin A or provitamin A composition.

### Claim 8 (depends on 1)

The process according to claim 1, wherein the at least one compound is at least 0.1 wt. % of the stabilized vitamin A or provitamin A composition.

### Claim 9 (depends on 2)

The process according to claim 2, wherein the triglycerides form an oil phase of the stabilized vitamin A or provitamin A composition, and the self-assembled structures are in the oil phase.

### Claim 10 (depends on 2)

The process according to claim 2, wherein the self-assembled structures are at least 0.05 wt. % of the stabilized vitamin A or provitamin A composition.

### Claim 11 (depends on 1)

The process according to claim 1, wherein the stabilized vitamin A or provitamin A composition is an emulsion.