Method for prophylaxis and/or treatment of ErbB2 positive cancers
AssigneeHealth Research, Inc.
InventorsYuesheng Zhang, Lu Yang, Yun Li
Life of this patent
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Abstract
Provided are compositions and methods for prophylaxis and/or therapy of ErbB2-positive cancer. The compositions include pharmaceutical preparations that contain isolated or recombinant or modified peptidase D (PEPD) proteins. The methods include prophylaxis and/or therapy of ErbB2-positive cancer by administering a PEPD to an individual who has or is at risk for developing ErbB2-positive cancer.
Claims8
A pharmaceutical preparation for use in prophylaxis and/or therapy of ErbB2-positive cancer comprising a chemotherapeutic agent and an isolated or recombinantly produced peptidase D (PEPD) and at least one pharmaceutically acceptable carrier, wherein the PEPD comprises SEQ ID NO:1 having a G278D change in said sequence.
A kit for use in prophylaxis and/or therapy of ErbB2-positive cancer comprising at least one sealed container which contains a pharmaceutical preparation comprising a chemotherapeutic agent and peptidase D (PEPD), wherein the PEPD comprises SEQ ID NO:1 having a G278D change in said sequence, and printed material which provides an indication that the pharmaceutical preparation is for use in prophylaxis and/or therapy of ErbB2-positive cancer in an individual.
Dependencies are inferred from the claim text.