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US 11,103,460 B2Granted
Fabrication methods for nanodelivery systems for long term controlled delivery of active pharmaceutical ingredients
AssigneeBoard of Regents, The University of Texas System
InventorsPaul S. Ho, Junjun Liu, Tengfei Jiang, Salomon A. Stavchansky
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Abstract
Embodiments of the present disclosure include devices, and methods of making such devices, for delivery of one or more active agents with short or long zero-order release kinetics. Embodiments also include implantable or injectable drug delivery systems capable of controlled release over long periods of time for therapeutic agents.
Claims18
A method of making a device for delivery of one or more active agents with short or long zero-order release kinetics, the method comprising:
- providing a substrate, and a plurality of non-planar enclosures, wherein the substrate comprises a first side and a second side;
- coupling the plurality of non-planar enclosures to the first side of the substrate;
- fabricating a plurality of apertures in the plurality of non-planar enclosures, wherein the plurality of apertures are fabricated via a maskless fabrication process;
- and
- loading the one or more active agents in the plurality of non-planar enclosures.
2 more elements
Dependencies are inferred from the claim text.