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US 11,090,285 B2Granted
Treatment of circadian rhythm disorders
AssigneeVanda Pharmaceuticals Inc.
InventorsMarlene Michelle Dressman, John Joseph Feeney, Louis William Licamele, Mihael H. Polymeropoulos
Life of this patent
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Abstract
Embodiments of the invention relate to the use of a melatonin agonist in the treatment of free running circadian rhythms in patients, including light perception impaired patients, e.g., blind patients, and to methods of measuring circadian rhythm.
Claims1
A method of administering tasimelteon to a patient who is being treated with rifampicin, the method comprising:
- maintaining the rifampicin treatment and administering to the patient a dose of tasimelteon that is greater than 20 mg/day, thereby avoiding reduced exposure to tasimelteon caused by induction of CYP3A4 by the rifampicin.
Dependencies are inferred from the claim text.