US 11,085,905 B2 · Techniques for monitoring chromatographic fluid flows

Abstract

Various embodiments are generally directed to techniques for monitoring chromatographic fluid flows, such as the flow to and/or from one or more reservoirs used in chromatographic operations, for instance. In many embodiments, the chromatographic operations may include one or more of High Performance Liquid Chromatography (HPLC), Ultra Performance Liquid Chromatography (UPLC), Ultra Performance Convergence Chromatography (UPC2), and the like. Several embodiments are particularly directed to a chromatographic fluid flow device (CFFD) for monitoring a change in density of a chromatographic fluid in a tube, such as by detecting the presence or absence of gas in the tube with an ultrasonic bubble detector. In various embodiments, the chromatographic fluid may include a solvent, a sample, or waste associated with a chromatographic operation.

Claims19

Dependent claims

A device for monitoring chromatographic fluid flow, comprising:

a reservoir coupler to attach to a reservoir comprising a chromatographic fluid;
a tube port to provide a tube with access to the reservoir, wherein the tube accesses the reservoir to establish fluid communication between the reservoir and the tube;
a transducer to monitor a change in density of the chromatographic fluid in the tube, the transducer to detect a presence or absence of a gas in the tube to monitor the change in density of the chromatographic fluid in the tube;
and
logic circuitry communicatively coupled to the transducer and a communication interface, the logic circuitry to communicate an indication via the communication interface based on the change in density of the chromatographic fluid monitored in the tube.

2 more elements

Dependencies are inferred from the claim text.

Techniques for monitoring chromatographic fluid flows

Life of this patent

Techniques for monitoring chromatographic fluid flows

Life of this patent

Abstract

Claims19