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AssigneeFraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e. V.
InventorsGuenter R. Fuhr, Heiko Zimmermann
Estimating the term…
The invention relates to a device for monitoring the temperature of a cryogenically preserved biological sample. The device (10) comprises a sample container (1) having a receptacle space (2) for accommodating a biological sample (6). The device further comprises at least one chamber (11), the interior (12) of which is not fluidically connected to the receptacle space, and which is at least partially filled with an indicator substance (7) having a boiling point or sublimation temperature in a range from −10° C. to −140° C. The chamber (11) further has at least one opening via which the indicator substance (7) can escape from the interior (12) of the chamber (11) upon exceeding its boiling point or sublimation point. The invention further relates to a method for monitoring the temperature of a cryogenically preserved biological sample.
A device for temperature monitoring of a cryopreserved biological sample, comprising
The method according to 13, wherein a parameter is determined which indicates a change in a quantity of indicator substance in the respective chamber and/or which indicates a measure for a period of time which the sample has spent at a temperature above the boiling temperature or the sublimation temperature of the indicator substance.
Dependencies are inferred from the claim text.