System and method for controlling electronic communications

A method for providing approved content from a controlled content repository, the method comprising:

• establishing an access protocol for a controlled content repository, wherein approved content is stored in the controlled content repository and is accessible according to the access protocol;
• providing the approved content in the controlled content repository to a first computing device after a determination that the approved content in the controlled content repository is authorized to be made available to the first computing device in accordance with the access protocol;
• receiving, at the controlled content repository, information about a first clinical endpoint, wherein the first clinical endpoint defines a first clinical study objective;
• receiving, at the controlled content repository, information about a second clinical endpoint, wherein the second clinical endpoint defines a second clinical study objective;
• and
• receiving, from the first computing device, first source data and second source data, wherein the first source data and the second source data are collected based on a statistic model.