Personalizing patient pathways based on individual preferences, lifestyle regime, and preferences on outcome parameters to assist decision making

A system for personalizing patient pathways, the system comprising:

• a display;
• one or more user input devices;
• and
• one or more processors programmed to:
• receive patient data relating to a patient's medical records;
• receive the patient's lifestyle values and preferences from the patient via the one or more user input devices;
• generate alternative options of patient pathway and treatment options using the patient data and the patient's lifestyle values and preferences including estimating probabilities of mortality and morbidity from the patient data, calculating probabilities of having long term impairments or disabilities based on the probabilities of morbidity, surveying the patient using time-trade-off to weigh the possible long-term impairments or disabilities, and calculating an expected quality-adjusted life years (QALYs) and confidence interval of the alternative choices using the time trade-off weighing the possible long-term impairments or disabilities;
• and
• generate a graphical tool that compares the alternative choices of pathway and treatment options including displaying, on the display, the alternative choices, QALYs, confidence intervals, and trends on health outcome including time of recovery, medical consequences, frequency and regime of treatment, lifestyle changes, and adverse effects;
• adjusting any one of the patient pathways and displaying the effect of that adjustment on the alternative choices, QALYs, confidence intervals, and trends of heath outcome;
• computing confidence intervals of the alternative outcomes based on the clinical evidences on outcomes, prognosis from similar populations, and personalized preferences on trading off quality of life and length of survival;
• and
• providing, on the graphical tool, best choices of pathways and treatment for the patient, wherein the best choices are based on the computed confidence intervals including providing a quantification of whether potential new information derived from an additional or new diagnostic test will help to determine the optimal treatment plan.