Method and apparatus for providing a pharmacokinetic drug dosing regimen

An apparatus comprising:

• a processor;
• a non-transitory storage medium comprising memory storing instructions that are configured, when executed by the processor, to cause the apparatus to perform a procedure comprising:
• determining, via the processor, an estimated pharmacokinetic profile of a patient using a Bayesian model of pharmacokinetic profiles of sampled patients, the estimated pharmacokinetic profile based upon at least one of a body weight or an age of the patient;
• determining, via the processor, a first dosing regimen for a first specified dosing interval including (i) a first dosage and (ii) a first therapeutic plasma protein level in the patient varying over time based at least upon the estimated pharmacokinetic profile;
• determining, via the processor, a second dosing regimen for a second specified dosing interval including (i) a second dosage and (ii) a second therapeutic plasma protein level in the patient varying over time based at least upon the estimated pharmacokinetic profile and in response to receiving a change to at least one of a minimum therapeutic plasma protein level, dosage interval, or dosage of the therapeutic plasma protein, wherein the change to the at least one of the minimum therapeutic plasma protein level, the dosage interval, or the dosage is received via a graphical user interface (GUI) associated with the apparatus that includes fields for user input for adjusting at least one of the minimum therapeutic plasma protein level, the dosage interval, or the dosage;
• displaying the second dosing regimen on a client device and within the GUI;
• adjusting, via the processor, the estimated pharmacokinetic profile of the patient upon previous treatments of the patient;
• and
• determining, via the processor, if the patient has a therapeutic plasma protein half-life greater than a predetermined threshold, wherein:
• a first weighting factor is applied to the Bayesian model of pharmacokinetic profiles of sampled patients if the half-life of the patient is greater than the predetermined threshold, and
• a second weighting factor, less than the first weighting factor, is applied to the Bayesian model of pharmacokinetic profiles of sampled patients if the half-life of the patient is less than the predetermined threshold.