# US 11,077,237 B2 · Constant pressure syringe for surgical use > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,077,237 B2 - Document ID: US11077237B2 - Status: Granted - Kind: B2 - Application number: 15/664,449 - Filed: 2017-07-31 - Published: 2018-05-17 - Granted: 2021-08-03 - Earliest claimed: 2006-10-06 - Assignees: Lipocosm, LLC - Applicants: Lipocosm LLC - Inventors: Roger K. Khouri; Murat Kuru - Web page: https://patentgrep.com/patent/US11077237B2 ## CPC - A61M 1/67: {Containers incorporating a piston-type member to create suction, e.g. syringes (cupping glasses A61M1/08; with a flexible member creating suction A61M1/68)} - A61M 1/71: {Suction drainage systems (containers therefor A61M1/60, A61M1/64; negative pressure wound therapy systems A61M1/90)} - A61M 1/84: {Drainage tubes; Aspiration tips (for negative pressure wound therapy A61M1/90; for surgical cutting instruments A61B17/32)} - A61M 1/87: {Details of the aspiration tip, not otherwise provided for} - A61M 1/89: {Suction aspects of liposuction (surgical cutting instruments A61B17/32)} - A61M 1/892: {with treatment of the collected fat} - A61M 1/895: {with means for reinjection of collected fat} - A61M 39/223: {Multiway valves} - A61M 1/81: {Piston pumps, e.g. syringes} - A61M 5/14216: {Reciprocating piston type} - A61M 5/1452: {pressurised by means of pistons} - A61M 39/24: Check- or non-return valves - A61M 2202/0021: removed from and reintroduced into the body, e.g. after treatment - A61M 2202/08: Lipoids - A61M 2205/073: Syringe, piston type - Y10T 137/7838: Plural - Y10T 137/87249: Multiple inlet with multiple outlet - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION ## Abstract A closed system for harvesting fat through liposuction, concentrating the aspirate so obtained, and then re-injecting the concentrated fat into a patient comprises as its main components a low pressure cannula having between about 7 to 12 side holes of about 1-2 mm by 2.0 to 4.0 mm, a spring loaded syringe holder with a constant force or coiled ribbon spring to apply a substantially constant pressure over the full excursion of the plunger, and a preferably flexible collection bag which is also preferably graduated, cylindrical over most of its body and funnel shaped at its bottom, all of which are connected through flexible tubings to a multi-port valve. The multi-port valve has two flutter/duck bill valves which restrict the fluid flow to a one way direction which effectively allows the syringe to be used to pump fat out of a patient and into a collection bag in a continuous manner. After the bags are centrifuged to concentrate the fat, the excess fluids are separated and the valve is re-connected to permit the syringe pump to reverse fluid flow to graft the concentrated fat back into the patient. ## Claims ### Claim 1 An aspirator/re-injector assembly, comprising: a receptacle configured to temporarily store a fat graft; a tube having at least a first end and a second end; and a multi-port valve, wherein the first end of the tube is configured to connect to the receptacle, wherein the second end of the tube is configured to connect to the multi-port valve, wherein the multi-port valve has a first port configured for a connection of a syringe and a second port configured for connection to a cannula, wherein the multi-port valve comprises at least one duck bill or flutter valve and is further configured for reinjecting a fat graft temporarily stored in the receptacle into the patient, wherein for injecting and for aspirating the syringe and cannula are in line along a same longitudinal axis. ### Claim 2 (depends on 1) The assembly of claim 1, wherein the receptacle is off axis from the longitudinal axis for reinjecting and aspirating. ### Claim 3 (depends on 1) The assembly of claim 1, wherein the a port for the receptacle is along an axis perpendicular to the longitudinal axis. ### Claim 4 (depends on 1) The assembly of claim 1, wherein the multi-port valve is configured for connecting to a 1-5 ml syringe. ### Claim 5 (depends on 1) The assembly of claim 1, wherein the first end of the tube is configured to connect to the receptacle through a luer lock connector. ### Claim 6 (depends on 1) The assembly of claim 1, wherein the second end of the tube is configured to connect to the multi-port valve through a luer lock connector. ### Claim 7 (depends on 1) The assembly of claim 1, wherein the multi-port valve is configured for connecting to the at least one of a syringe and a cannula through a luer lock connector. ### Claim 8 (depends on 1) The assembly of claim 1, wherein the multi-port valve is configured to permit one-way flow of a fat graft from the receptacle, through the tube, and into a patient. ### Claim 9 (depends on 1) The assembly of claim 1, wherein the multi-port valve is configured to permit continuous flow of a fat graft from the receptacle, through the tube, and into the patient. ### Claim 10 (depends on 1) The assembly of claim 1, wherein the multi-port valve is configured to allow at least one of automatic and continuous refilling of a syringe with fat graft material from the receptacle during use after each reinjection into a patient. ### Claim 11 (depends on 1) A method of continuously grafting lipoaspirated fat into a subject in need thereof, comprising operating the assembly of claim 1 to achieve continuous one-way flow of a fat graft: (i) from the receptacle through the tube and into a syringe, and (ii) from the syringe through a cannula and into the subject's body. ### Claim 12 (depends on 11) The method of claim 11, wherein said operation comprises: (i) inserting the cannula into the subject's body; (ii) operating the syringe to withdraw the fat graft from the receptacle through the tube, and into the syringe; (iii) operating the syringe to deposit the fat graft from the syringe into the subject's body through the cannula; and (iv) repeating steps (ii) and (iii) one or more times. ### Claim 13 (depends on 1) The assembly of claim 1, further comprising the receptacle, the receptacle comprising a collapsible bag forming a low speed centrifuge tube. ### Claim 14 (depends on 1) The assembly of claim 1, further comprising the receptacle, the receptacle comprising a concentration device that allows purging out of separated serum at a bottom and free oil and accumulated air at the top. ### Claim 15 (depends on 14) The assembly of claim 14, wherein the receptacle further comprises a port at the bottom and a port at the top. ### Claim 16 (depends on 1) The assembly of claim 1, further comprising the receptacle, the receptacle enabling venting of excess aspirated air. ### Claim 17 (depends on 1) The assembly of claim 1, further comprising the cannula, the cannula having multiple series of holes aligned along a length.