Methods for preparing squalene
AssigneeNovartis AG
InventorManinder Hora
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Abstract
An improved method for preparing squalene from a squalene-containing composition, said method comprising the steps of (a) a purification distillation carried out at a temperature T1 (b) a denaturing distillation carried out at a temperature T2; wherein steps (a) and (b) may be performed in either order; T1 and T2 are sufficient to cause squalene to boil; T2>T1; and T2>200° C.
Claims18
A method for preparing squalene from a composition comprising squalene from an animal source, said method comprising steps of (a) a purification distillation carried out at a temperature T1, (b) a denaturing distillation carried out at a temperature T2 and at a pressure of from 0.5 mm Hg to 5.0 mm Hg;
- wherein steps (a) and (b) may be performed in either order;
- T1 and T2 are sufficient to cause squalene to boil;
- T2>T1;
- and T2≥200° C.
A method for re-distillation of a composition comprising 99% squalene or more, said method comprising:
- (i) providing a squalene-containing composition comprising 99% squalene or more from an animal source, wherein said squalene-containing composition has been obtained by a process of purification distillation carried out at a temperature T1;
- and
- (ii) subjecting the composition from (i) to a re-distillation, said re-distillation being a denaturing distillation carried out at a temperature T2;
- wherein T2≥200° C.
Dependencies are inferred from the claim text.