# US 11,077,152 B2 · Method of producing nasal drop composition by mixing earthworm castings with water

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- Number: US 11,077,152 B2
- Document ID: US11077152B2
- Status: Granted
- Kind: B2
- Application number: 16/485,220
- Filed: 2018-03-16
- Published: 2019-12-05
- Granted: 2021-08-03
- Earliest claimed: 2017-03-21
- Assignees: Well Stone Co.
- Applicants: Well Stone Co.
- Inventors: Yoichi Ishii; Takeshi Okamoto; Sayaka Makino
- Web page: https://patentgrep.com/patent/US11077152B2

## CPC

- A61K 35/62: Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
- A61K 9/0043: {Nose}
- A61K 36/13: Coniferophyta (gymnosperms)
- A61P 11/12: Mucolytics
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

Provided are: a method for producing a nasal drop composition suitable for treatment or prevention of a disease or symptom in the nasal cavities; and a nasal drop composition produced by the production method. The nasal drop composition production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the nasal drop composition produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.

## Claims

### Claim 1

A method of producing a nasal drop composition comprising:
mixing earthworm castings with water to obtain a mixture; and
collecting vaporized water generated from the mixture to obtain a liquid as the nasal drop composition.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the mixing further comprises mixing an organic substance together with the earthworm castings and the water.

### Claim 3 (depends on 2)

The method according to claim 2, wherein the organic substance is a wood material.

### Claim 4 (depends on 1)

The method according to claim 1, further comprising diluting the liquid with water to obtain the nasal drop composition.