# US 11,077,052 B1 · Selected multi-phase treatment for coronavirus respiratory infections > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,077,052 B1 - Document ID: US11077052B1 - Status: Granted - Kind: B1 - Application number: 17/016,300 - Filed: 2020-09-09 - Granted: 2021-08-03 - Earliest claimed: 2020-09-09 - Applicants: Malireddy S. Reddy - Inventors: Malireddy S. Reddy - Web page: https://patentgrep.com/patent/US11077052B1 ## CPC - A61K 9/0043: {Nose} - A61K 9/127: Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant - A61K 31/658: {o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol} - A61K 35/741: Probiotics (probiotic yeast, e.g. saccharomyces A61K36/06) - A61K 35/742: Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes - A61K 35/744: Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs - A61K 35/745: Bifidobacteria - A61K 35/747: Lactobacilli, e.g. L. acidophilus or L. brevis - A61K 36/064: Saccharomycetales, e.g. baker's yeast - A61K 36/53: Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender - A61K 36/61: Myrtaceae (Myrtle family), e.g. teatree or eucalyptus - A61K 36/9066: Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger - A61K 47/02: Inorganic compounds - A61K 47/22: Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones - A61K 47/42: Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein (oligopeptides having up to five amino acids {A61K47/183}; polyamino acids A61K47/34) - A61P 31/14: for RNA viruses - A61K 2035/115: {Probiotics} - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS ## Abstract A multi-phase treatment of a respiratory disease in which one treatment is a lysing defense by applying inhibitory agents to respiratory passages. Application may be by nasal irrigant, oral gargling mouthwash, or smelling salt. Another treatment is an immune system suppressing defense by providing a liposome-based countermeasure to excess activity of the host immune system during COVID-19 infection. The liposome increases bio-activity of probiotics, probiotics-produced therapeutic peptides, bio-peptides, and antioxidant level in the blood with a sustained massive dose of antioxidants to counteract excess oxidation produced by excess activity of the host immune system, when administered through oral route. ## Claims ### Claim 1 A method of treating SARS-CoV-2 coronavirus infection by administering to a human subject in need thereof an effective amount of a preparation of: a combination of viable probiotics comprising Lactococcus lactis subsp. lactis, Lactobacillus sporogenes, Streptococcus thermophilus; and immunomodulins of said viable probiotics. ### Claim 2 (depends on 1) The method of claim 1, wherein said preparation further comprises an herbal extract that is a stimulant of said viable protiotics. ### Claim 3 (depends on 2) The method of claim 2, wherein said herbal extract is a combination of clove, turmeric, and basil. ### Claim 4 (depends on 1) The method of claim 1, wherein said preparation is administered by a sinus flush. ### Claim 5 (depends on 1) The method of claim 1, wherein said preparation is administered by smelling salt, and the smelling salt comprises sodium hypochlorite solution. ### Claim 6 (depends on 5) The method of claim 5, wherein said smelling salt further comprises cannabidiol. ### Claim 7 (depends on 5) The method of claim 5, wherein said smelling salt further comprises ammonium carbonate. ### Claim 8 (depends on 5) The method of claim 5, wherein said smelling salt further comprises chloroform. ### Claim 9 A method of treating SARS-CoV-2 coronavirus infection by administering to a subject in need thereof, said subject chosen among human, dog, or cat, an effective amount of a preparation comprising: a liposome of a viable probiotic, wherein the said viable probiotic is a combination of Lactococcus lactis subsp. lactis, Lactobacillus sporogenes, and Streptococcus thermophilus, and immunomodulins of said viable probiotic. ### Claim 10 (depends on 9) The method of claim 9, wherein said preparation further comprises: protectants and stimulants of said viable probiotic and of said immunomodulins. ### Claim 11 (depends on 9) The method of claim 9, wherein said preparation further comprises: an herbal extract that is a stimulant of said viable probiotic. ### Claim 12 (depends on 11) The method of claim 11, wherein said herbal extract further comprises stimulants of said viable probiotic and of said immunomodulins within said liposome, said stimulants comprising: a combination of clove, turmeric, and basil. ### Claim 13 (depends on 9) The method of claim 9, wherein said preparation further comprises protectants of said viable probiotic and of said immunomodulins within said liposome, said protectants comprising: polysorbate; natamycin; sodium propionate; and glucose oxidase. ### Claim 14 (depends on 9) The method of claim 9, wherein said preparation further comprises buffering agents of said viable probiotic and of said immunomodulins within said liposome, said buffering agents comprising: ascorbic acid; sodium bicarbonate; sodium ascorbate; and sodium chloride. ### Claim 15 (depends on 10) The method of claim 10, wherein: said preparation is administered by a sinus flush. ### Claim 16 (depends on 1) The method of claim 1, wherein said preparation further comprises: protectants and stimulants of said probiotics and said immunomodulins.