# US 11,077,036 B2 · Lactam solubility

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- Number: US 11,077,036 B2
- Document ID: US11077036B2
- Status: Granted
- Kind: B2
- Application number: 15/750,901
- Filed: 2016-07-28
- Published: 2020-03-19
- Granted: 2021-08-03
- Earliest claimed: 2015-08-20
- Assignees: Conopco, Inc.
- Applicants: Conopco, Inc.
- Inventors: Paul Damien Price; Neil James Parry
- Web page: https://patentgrep.com/patent/US11077036B2

## CPC

- A61K 8/37: Esters of carboxylic acids
- A01N 43/36: five-membered rings
- A61K 8/4913: {having five membered rings, e.g. pyrrolidone carboxylic acid}
- A61Q 17/005: {Antimicrobial preparations}
- A61Q 19/00: Preparations for care of the skin
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

Compositions comprising a lactam and an alkyl lactate. The compositions are suitable for use as anti-microbial, anti-biofilm and bacteriostatic compositions.

## Claims

### Claim 1

A composition comprising a lactam and an ethyl lactate, wherein the lactam is 4-(4-chlorophenyl)-5-methylene-pyrrol-2-one of Formula I:
wherein the lactam is dissolved in the composition;
wherein the amount of ethyl lactate is 0.01 to 10% wt. of the composition; and
wherein the composition is at least 60 wt % water.

### Claim 2 (depends on 1)

The composition of claim 1, wherein the composition is at least 70 wt % water.

### Claim 3 (depends on 1)

The composition of claim 1, wherein the composition is an aqueous composition.

### Claim 4 (depends on 1)

The composition of claim 1, wherein the composition is a homecare composition.

### Claim 5 (depends on 1)

The composition of claim 1, wherein the composition is a personal care composition.

### Claim 6 (depends on 1)

The composition of claim 1, wherein the amount of ethyl lactate is 0.01 to 5% wt. of the composition.

### Claim 7 (depends on 1)

The composition of claim 1, wherein the amount of ethyl lactate is 0.01 to 3% wt. of the composition.

### Claim 8 (depends on 1)

The composition of claim 1, wherein the amount of ethyl lactate is 0.01 to 1% wt. of the composition.

### Claim 9 (depends on 1)

The composition of claim 1, wherein the amount of ethyl lactate is 0.001 to 1% wt. of the composition and the composition is an aqueous composition.

### Claim 10 (depends on 1)

The composition of claim 1, wherein the composition comprises 0.000001 to 5% wt. lactam.

### Claim 11 (depends on 1)

The composition of claim 1, wherein the composition comprises 0.001 to 5% wt. lactam.

### Claim 12 (depends on 1)

The composition of claim 1, wherein the composition comprises 0.01 to 2% wt. lactam.