# US 11,077,021 B2 · Two-chamber carpule > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,077,021 B2 - Document ID: US11077021B2 - Status: Granted - Kind: B2 - Application number: 16/076,242 - Filed: 2017-02-09 - Published: 2019-08-29 - Granted: 2021-08-03 - Earliest claimed: 2016-02-09 - Assignees: Sanofi-Aventis Deutschland GmbH - Applicants: Sanofi-Aventis Deutschland GMBH - Inventors: Bernd Kühn; Jörn Möckel; Werner Seiferlein - Web page: https://patentgrep.com/patent/US11077021B2 ## CPC - A61J 1/2093: {Containers having several compartments for products to be mixed} - A61J 1/062: {Carpules} - A61J 1/065: {Rigid ampoules, e.g. glass ampoules} - A61J 1/2041: {having removable plugs} - A61M 5/2066: {comprising means for injection of two or more media, e.g. by mixing} - A61M 5/2448: {comprising means for injection of two or more media, e.g. by mixing} - A61M 5/284: {comprising means for injection of two or more media, e.g. by mixing} - A61M 5/3129: {Syringe barrels (A61M5/3205, A61M5/50 take precedence)} - B65B 3/003: {Filling medical containers such as ampoules, vials, syringes or the like} - B65B 29/10: Packaging two or more different substances isolated from one another in the package but capable of being mixed without opening the package, e.g. forming packages containing a resin and hardener isolated by a frangible partition - A61J 1/1412: {Containers with closing means, e.g. caps} - A61J: CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - B65B: MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING (bundling and pressing devices for cigars A24C1/44; devices for tensioning and securing binders adapted to be supported by the article or articles to be bound B25B25/00; applying closure members to bottles, jars or similar containers B67B1/00-B67B6/00; concurrent cleaning, filling and closing of bottles B67C7/00; emptying bottles, jars, cans, casks, barrels or similar containers B67C9/00) ## Abstract The disclosure provides a two-chamber carpule comprising two-chambers adapted to be joined together. Each chamber is adapted to contain a medicament component. The carpule further comprises a bevel arranged on a circumference of at least one of the chambers in a transition area. The bevel extends from one chamber to the other chamber. ## Claims ### Claim 1 A two-chamber carpule comprising: a first chamber and a second chamber adapted to be joined together, each chamber adapted to contain a medicament component, the first and second chambers formed by respective separate first and second components, the separate first and second components being axially joined together, and a bevel arranged on an inner circumference of at least one of the first and second components in a transition area, extending from the first component to the second component, wherein the transition area provides an edge to block a movement of a plug in a determined direction. ### Claim 2 (depends on 1) The two-chamber carpule according to claim 1, wherein the edge is formed by a distal end of the first component that comprises an inner diameter less than an inner diameter of the second component in the transition area, due to the bevel. ### Claim 3 (depends on 2) The two-chamber carpule according to claim 2, wherein at least one section of an inner circumference of the second component is bevelled such that the inner diameter of the second component decreases in a direction away from the first component. ### Claim 4 (depends on 3) The two-chamber carpule according to claim 3, wherein the inner diameter of the first component is less than or equal to the inner diameter of the second component having the bevel. ### Claim 5 (depends on 1) The two-chamber carpule according to claim 1, wherein at least one section of an inner circumference of the first component is bevelled such that an inner diameter of the first component decreases in a direction facing the second component. ### Claim 6 (depends on 1) The two-chamber carpule according to claim 1, wherein the second component is made from a plastic material and the first component is made from a glass material. ### Claim 7 (depends on 1) The two-chamber carpule according to claim 1, wherein the first and second components are made from a glass material or from a plastic material. ### Claim 8 (depends on 1) The two-chamber carpule according to claim 1, wherein the first and second components are axially joined together by a bayonet fitting comprising at least one protrusion and a corresponding slot. ### Claim 9 (depends on 1) The two-chamber carpule according to claim 1, wherein the first and second components are axially joined together by a snap fitting comprising at least one locking arm and a corresponding locking projection. ### Claim 10 (depends on 1) The two-chamber carpule according to claim 1, wherein the first and second components are axially plugged together. ### Claim 11 (depends on 10) The two-chamber carpule according to claim 10, wherein the first and second components respectively comprise a rough surface in an interface area of the plugged first and second components. ### Claim 12 (depends on 10) The two-chamber carpule according to claim 10, wherein a clamp element is arranged between the plugged first and second components. ### Claim 13 (depends on 1) The two-chamber carpule according to claim 1, wherein a sealing element is arranged between the axially joined components. ### Claim 14 (depends on 1) A method of assembly of the two-chamber carpule according to claim 1, the method comprising: joining the first chamber and the second chamber in a force fitting, form fitting, or firmly bonding manner. ### Claim 15 (depends on 14) The method according to claim 14, comprising: manufacturing the first component and the second component, wherein the first component forms the first chamber and the second component forms the second chamber, filling the first component with a medicament component and closing the first component, axially joining the first and second components, and filling the second component with a medicament component and closing the second component. ### Claim 16 (depends on 15) The method according to claim 15, wherein closing the first component comprises: inserting at least one plug into the chamber. ### Claim 17 (depends on 15) The method according to claim 15, wherein axially joining the first and second components comprises force fitting the first and second components. ### Claim 18 (depends on 15) The method according to claim 15, wherein axially joining the first and second components comprises form fitting the first and second components. ### Claim 19 (depends on 15) The method according to claim 15, wherein axially joining the first and second components comprises firmly bonding the first and second components. ### Claim 20 A two-chamber carpule comprising: a first chamber and a second chamber adapted to be joined together, each chamber adapted to contain a medicament component, the first and second chambers formed by respective separate first and second components, the separate first and second components being axially joined together, and a bevel arranged on an inner circumference of at least one of the first and second components in a transition area, extending from the first component to the second component, wherein the transition area provides an edge to block a movement of a plug in a determined direction, wherein a length of the bevel is larger than a distance between the edge and the bevel.