Implantable prosthetic heart valve

A prosthetic heart valve, comprising:

• a support stent having an inlet end portion and an outlet end portion, wherein the support stent is configured to be radially expandable from a crimped configuration to an expanded configuration;
• a valve assembly comprising an inlet, an outlet, and a plurality of leaflets that are moveable between an open position and a closed position, wherein the leaflets in the open position are configured to permit fluid flow from the inlet to the outlet and the leaflets in the closed position are configured to block fluid flow from the outlet to the inlet;
• and
• a connection structure that supports the valve assembly in the support stent such that the inlet of the valve assembly is spaced radially inwardly of the support stent and forms an annular space between an inner surface of the support stent and the valve assembly at the inlet of the valve assembly when the support stent is in the expanded configuration, wherein the annular space has a width in a radial direction between 0.5 cm and 3 cm, wherein the connection structure comprises a connecting membrane extending radially inwardly from the support stent to the valve assembly.

A prosthetic heart valve, comprising:

• a support stent having an inlet end portion and an outlet end portion, wherein the support stent is configured to be radially expandable from a crimped configuration to an expanded configuration;
• a valve assembly comprising an inlet, an outlet, and a plurality of leaflets that are moveable between an open position and a closed position, wherein the leaflets in the open position are configured to permit fluid flow from the inlet to the outlet and the leaflets in the closed position are configured to block fluid flow from the outlet to the inlet;
• and
• a connection structure that supports the valve assembly in the support stent such that the inlet of the valve assembly is spaced radially inwardly of the support stent and forms an annular space between an inner surface of the support stent and the valve assembly at the inlet of the valve assembly when the support stent is in the expanded configuration, wherein the annular space has a width in a radial direction between 0.5 cm and 3 cm,
• wherein an entire outer surface of the valve assembly is spaced radially inwardly of the support stent and does not directly contact the support stent when the support stent is in the expanded configuration.

A prosthetic heart valve, comprising:

• a support stent having an inlet end portion and an outlet end portion, wherein the support stent is configured to be radially expandable from a crimped configuration to an expanded configuration;
• a valve assembly comprising an inlet, an outlet, and a plurality of leaflets that are moveable between an open position and a closed position;
• and
• a connection structure that supports the valve assembly in the support stent such that the inlet of the valve assembly is spaced radially inwardly of the support stent and does not directly contact the support stent when the support stent is in the expanded configuration,
• wherein when the leaflets are in the open position, free edges of the leaflets form a concentric ring about a longitudinal axis of the valve assembly so that fluid is permitted to flow from an inlet to an outlet of the valve assembly, wherein when the leaflets are in the closed position, edges of the leaflets collapse inwardly to form a tricuspid configuration so as to block fluid flow from the outlet to the inlet of the valve assembly,
• wherein an outer surface of the valve assembly has a cylindrical shape,
• wherein the outer surface of the valve assembly and an inner surface of the support stent is separated by a radial distance between 0.5 cm and 3 cm when the support stent is in the expanded configuration,
• wherein the valve assembly has a cross-sectional area from about 40% to 80% of a cross-sectional area of the support stent across a midsection of the support stent.