# US 11,076,952 B2 · Collapsible atrioventricular valve prosthesis > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,076,952 B2 - Document ID: US11076952B2 - Status: Granted - Kind: B2 - Application number: 15/598,210 - Filed: 2017-05-17 - Published: 2017-09-07 - Granted: 2021-08-03 - Earliest claimed: 2013-06-14 - Assignees: The Regents of the University of California - Applicants: The Regents of the University of California - Inventors: Arash Kheradvar - Web page: https://patentgrep.com/patent/US11076952B2 ## CPC - A61F 2/2412: {with soft flexible valve members, e.g. tissue valves shaped like natural valves} - A61F 2/2418: {Scaffolds therefor, e.g. support stents} - A61F 2/2436: {Deployment by retracting a sheath} - A61F 2210/0014: using shape memory or superelastic materials, e.g. nitinol - A61F 2220/0008: Fixation appliances for connecting prostheses to the body - A61F 2220/0075: sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable - A61F 2230/0013: Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped - A61F 2230/0095: Saddle-shaped - A61F 2250/0063: Nested prosthetic parts - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract This disclosure is directed to a collapsible atrioventricular valve prosthesis. The valve includes an annulus wire frame having at least two prongs extending therefrom. At least one catch is formed between each of the prongs and leaflets are attached with the frame, catch, and prongs form the valve. The prongs project a first direction and the catch projects in a direction away from the prongs. The valve is collapsible to provide for easy delivery to an atrioventricular junction or other desired location within a heart. Once deployed, the valve can expand with the catches acting to hold the annulus frame secure on an atrioventricular junction, at a ventricular side or at an atrial side of a heart. ## Claims ### Claim 1 A collapsible atrioventricular valve, comprising: an annulus frame, wherein the annulus frame includes three prongs extending therefrom, with at least one catch positioned on the annulus frame between each of the three prongs, and wherein each prong is comprised of two wire-form structures constrained together by a hypo tube wrapped and permanently affixed around the two wire-form structures; at least two leaflets attached with the annulus frame and prongs to form a valve; and wherein the annulus frame is a saddle-shaped annulus having a crest reflecting curvature of the saddle-shaped annulus. ### Claim 2 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, where the annulus frame further comprises at least one catch that acts to hold the annulus frame secure on an atrioventricular junction or at an atrial or ventricular side of a heart, the catch projecting from the annulus frame directly beneath the crest, whereby when implanted the collapsible atrioventricular valve lies between a heart's atrium and ventricle. ### Claim 3 (depends on 2) The collapsible atrioventricular valve as set forth in in claim 2, wherein the prongs project from the annulus frame in a first direction and the at least one catch projects from the annulus frame in a direction away from the first direction. ### Claim 4 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the annulus frame is symmetric. ### Claim 5 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the annulus frame is axisymmetric. ### Claim 6 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, where the annulus frame is asymmetric. ### Claim 7 (depends on 1) The collapsible atrioventricular valve as set forth in claim 1, wherein the hypo tube has at least one hole that can be used for attachment to a delivery system. ### Claim 8 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the valve is collapsible with a delivery system for percutaneous heart valve delivery. ### Claim 9 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the annular frame is made of a monolithic wire. ### Claim 10 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the annular frame is formed of a plurality of frame subcomponents. ### Claim 11 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the annular frame is formed of shape-memory material selected from a group consisting of Nitinol, Cobalt-Chromium and polymers. ### Claim 12 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the valve is configurable between a collapsed configuration and an open configuration, such the collapsed configuration allows the valve to be delivered into position against a native atrioventricular valve annulus and upon expanding to the open configuration, the atrioventricular valve is secured in place by the at least one catch. ### Claim 13 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the leaflets are formed of a material selected from a group consisting of pericardial tissue, polymeric material, and leaflet tissue material. ### Claim 14 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein a surface of the annular frame is rough, thereby accommodating improved sitting at an atrioventricular junction. ### Claim 15 (depends on 14) The collapsible atrioventricular valve as set forth in in claim 14, wherein the annular frame is a wire frame and the surface of the annular frame is rough due to external components added to the wire frame. ### Claim 16 (depends on 14) The collapsible atrioventricular valve as set forth in in claim 14, wherein the annular frame is a wire frame and the surface of the annular frame is rough due to an inherent roughness of the wire frame. ### Claim 17 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, further comprising a periphery skirt attached to a circumference of the annular frame, whereby the periphery skirt serves to minimize paravalvular leakage once implanted in a patient. ### Claim 18 (depends on 17) The collapsible atrioventricular valve as set forth in in claim 17, wherein the periphery skirt is formed of a material selected from a group consisting of pericardial tissue, polymeric material, and leaflet tissue material. ### Claim 19 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the valve is collapsible and is deliverable to heart chambers via transapical approach. ### Claim 20 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the valve is collapsible and is deliverable to heart chambers through peripheral vasculature, comprising transfemoral artery/vein, aorta/vena cava, subclavian vasculature or jugular veins. ### Claim 21 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the valve is collapsible and is deliverable to heart chambers via surgical procedures comprising, thoracotomy, mini-thoracotomy and minimally invasive heart surgery. ### Claim 22 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the annulus frame includes five catches, such that one catch is positioned on the annulus frame between a first set of adjacent prongs, and two catches are positioned on the annulus frame between a second set of adjacent prongs, and two catches are positioned on the annulus frame between a third set of adjacent prongs. ### Claim 23 (depends on 1) The collapsible atrioventricular valve as set forth in in claim 1, wherein the annulus frame includes four catches, such that one catch is positioned on the annulus frame between a first set of adjacent prongs, and one catch is positioned on the annulus frame between a second set of adjacent prongs, and two catches are positioned on the annulus frame between a third set of adjacent prongs.