# US 11,076,783 B2 · Medical monitoring optical computing device

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 11,076,783 B2
- Document ID: US11076783B2
- Status: Granted
- Kind: B2
- Application number: 15/034,635
- Filed: 2013-12-30
- Published: 2016-10-06
- Granted: 2021-08-03
- Earliest claimed: 2013-12-30
- Assignees: Halliburton Energy Services, Inc.
- Applicants: Halliburton Energy Services, Inc.
- Inventors: David L. Perkins; Gregory Powers
- Web page: https://patentgrep.com/patent/US11076783B2

## CPC

- A61B 5/1455: using optical sensors, e.g. spectral photometrical oximeters
- A61B 5/14507: {specially adapted for measuring characteristics of body fluids other than blood (devices for taking samples of body liquids A61B10/0045)}
- A61B 5/14546: {for measuring analytes not otherwise provided for, e.g. ions, cytochromes}
- A61B 5/441: {Skin evaluation, e.g. for skin disorder diagnosis}
- A61B 5/6801: {specially adapted to be attached to or worn on the body surface}
- A61B 5/7405: {using sound}
- A61B 5/742: {using visual displays (displays for heart-related electrical signals, e.g. ECG, A61B5/339)}
- G01N 21/31: Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry {(G01N21/72 takes precedence)}
- G01N 21/8483: {Investigating reagent band (test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04)}
- G01N 33/49: Blood {(chemical methods for determining blood cell populations G01N33/5094; chemical analysis of blood groups or blood types G01N33/80)}
- G01N 33/497: of gaseous biological material, e.g. breath
- G01N 2201/0222: Pocket size
- Y02A 50/30: Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE

## Abstract

Various embodiments of optical computing devices utilized in healthcare-related applications.

## Claims

### Claim 1

A method for medical monitoring utilizing an optical computing device, the method comprising:
optically interacting electromagnetic radiation with a sample to produce sample-interacted light;
optically interacting the sample-interacted light with a multivariate optical calculation device forming part of the optical computing device, the multivariate optical calculation device having an Integrated Computational Element (“ICE”) core and being positioned to perform a regression calculation on the sample-interacted light to thereby produce a signal which corresponds to at least one medical characteristic of the sample;
determine at least one medical characteristic of the sample using the signal, wherein the optical computing device is an antigen-based rapid diagnostic test (“RDT”) device;
determine, using the multivariate optical calculation device, whether the antigen-based RDT device is temperature damaged or water damaged; and
responsive to a determination the antigen-based RDT device is temperature or water damaged, correcting the signal.

### Claim 2 (depends on 1)

An optical computing method as defined in claim 1, wherein:
the sample is food; and
the signal corresponding to the medical characteristic indicates the presence of allergens or sugars.

### Claim 3 (depends on 1)

An optical computing method as defined in claim 1, further comprising communicating an alert signal based upon the signal that corresponds to the medical characteristic of the sample.

### Claim 4 (depends on 3)

An optical computing method as defined in claim 3, further comprising communicating the alert signal as a visual or audible alert.

### Claim 5 (depends on 1)

An optical computing method as defined in claim 1, wherein the optical computing device forms part of a portable device having a display, the method further comprising:
optically interacting the sample-interacted light with the ICE core positioned within the multivariate optical calculation device to produce optically-interacted light, the ICE core being configured to be associated with the medical characteristic of the sample;
detecting the optically-interacted light with a detector and thereby generating the signal corresponding to the medical characteristic of the sample; and
displaying data related to the medical characteristic on the display.

### Claim 6 (depends on 1)

An optical computing method as defined in claim 1, wherein:
the optical computing device forms part of a dialysis machine; and
the sample is blood.

### Claim 7 (depends on 1)

An optical computing method as defined in claim 1, wherein the optical computing device forms part of a breathalyzer machine, the sample being breathe particles.

### Claim 8 (depends on 1)

An optical computing method as defined in claim 1, wherein the optical computing device forms part of a skin analysis device, the method further comprising:
optically interacting the electromagnetic radiation with skin to produce the sample-interacted light;
optically interacting the sample-interacted light with the ICE core positioned within the multivariate optical calculation device to produce optically-interacted light, the ICE core being configured to be associated with the medical characteristic of the sample; and
detecting the optically-interacted light with a detector and thereby generating the signal corresponding to the medical characteristic of the sample.

### Claim 9 (depends on 8)

An optical computing method as defined in claim 8, wherein the sample is skin or blood within the skin.

### Claim 10 (depends on 9)

An optical computing method as defined in claim 9, wherein the optical computing device is worn on the skin.

### Claim 11 (depends on 1)

An optical computing device to perform the method of claim 1.

### Claim 12

An optical computing device utilized for medical monitoring, the device comprising:
a housing; and
a multivariate optical calculation device inside the housing having an Integrated Computational Element (“ICE”) core and positioned to perform a regression calculation on sample-interacted light to thereby produce a signal which corresponds to at least one medical characteristic of a sample, wherein at least one medical characteristic of the sample is determined using the signal,
wherein the optical computing device is an antigen-based rapid diagnostic test (“RDT”) device, and
wherein the optical computing device determines, using the multivariate optical calculation device, whether the antigen-based RDT device is temperature damaged or water damaged and responsive to a determination the antigen-based RDT device is temperature or water damaged, correcting the signal.

### Claim 13 (depends on 12)

An optical computing device as defined in claim 12, further comprising:
a display to display data related to the medical characteristic; or
a mechanism to generate an alert signal corresponding to the medical characteristic.

### Claim 14 (depends on 12)

An optical computing device as defined in claim 12, wherein:
the housing is handheld; and
the multivariate optical calculation device comprises:
one or more channels in which to place the sample;
an electromagnetic radiation source to produce light which optically interacts with the sample positioned within the channel to generate the sample-interacted light;
the ICE core positioned to optically interact with the sample-interacted light to thereby produce optically-interacted light, the ICE core being associated with the medical characteristic of the sample; and
a detector positioned to measure the optically-interacted light and thereby generate a signal utilized to determine the medical characteristic of the sample.

### Claim 15 (depends on 12)

An optical computing device as defined in claim 12, wherein the sample is placed on a testing strip positioned along the one or more channels.

### Claim 16 (depends on 12)

An optical computing device as defined in claim 12, wherein:
the housing comprises a viewing optic through which to view the sample and an indicator of the medical characteristic; and
the multivariate optical calculation device positioned along the viewing optic, the multivariate optical calculation device comprising the ICE core positioned to optically interact with sample-interacted light to thereby produce optically-interacted light to be viewed by a human eye, the ICE core being associated with the medical characteristic of the sample.

### Claim 17 (depends on 16)

An optical computing device as defined in claim 16, wherein the viewing optic forms part of facial glasses.