# US 11,076,618 B2 · Feed additive composition for ruminants

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- Number: US 11,076,618 B2
- Document ID: US11076618B2
- Status: Granted
- Kind: B2
- Application number: 16/394,594
- Filed: 2019-04-25
- Published: 2019-08-15
- Granted: 2021-08-03
- Earliest claimed: 2016-10-27
- Assignees: Ajinomoto Co., Inc.
- Applicants: Ajinomoto Co., Inc.
- Inventors: Susumu Shibahara; Sachiko Yonemaru; Koji Haga; Yuki Miyazawa; Takaaki Sato
- Web page: https://patentgrep.com/patent/US11076618B2

## CPC

- A23K 50/10: for ruminants
- A23K 10/20: from material of animal origin (obtained by microbiological or biochemical processes A23K10/10)
- A23K 10/30: from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms (obtained by microbiological or biochemical processes, e.g. using yeasts or enzymes, A23K10/10)
- A23K 20/142: Amino acids; Derivatives thereof
- A23K 20/158: Fatty acids; Fats; Products containing oils or fats
- A23K 20/174: Vitamins
- A23K 40/30: by encapsulating; by coating
- A23K: FODDER

## Abstract

Feed additive compositions for ruminants containing (A) at least one member selected from the group consisting of hydrogenated vegetable oil and hydrogenated animal oil each having a melting point of higher than 50° C. and lower than 90° C.; (B) not less than 0.05 wt % and not more than 6 wt % of lecithin; (C) not less than 30 wt % and less than 65 wt % of a biologically active substance; (D) not less than 0.01 wt % and less than 0.8 wt % of a natural vegetable oil; and not less than 0.1 wt % and less than 6 wt % of water exhibit high protection in the rumen and are also superior in dissolution in the lower gastrointestinal tract.

## Claims

### Claim 1

A feed additive composition for ruminants to protect nutrients in the rumen and make the nutrients available for absorption in the gastrointestinal track after the fourth stomach, the composition comprising:
(A) at least one selected from the group consisting of hydrogenated vegetable oil and hydrogenated animal oil each having a melting point of from higher than 50° C. to lower than 90° C.;
(B) from 0.05 wt % to 6 wt %, based on the total weight of the composition, of lecithin;
(C) from 30 wt % to less than 65 wt %, based on the total weight of the composition, of a biologically active substance;
(D) from 0.01 wt % to less than 0.8 wt %, based on the total weight of the composition, of a natural vegetable oil; and
from 0.1 wt % to less than 6 wt %, based on the total weight of the composition, of water,
wherein the feed additive composition comprises a surface layer substantially free of the biologically active substance.

### Claim 2 (depends on 1)

The composition according to claim 1, wherein the amount of the natural vegetable oil (D) is from 0.1 wt % to 0.4 wt %, based on the total weight of the composition.

### Claim 3 (depends on 2)

The composition according to claim 2, wherein the natural vegetable oil (D) comprises from 60 wt % to 95 wt % of an unsaturated fatty acid, relative to the total content of fatty acids in the natural vegetable oil (D), having 18 carbon atoms.

### Claim 4 (depends on 2)

The composition according to claim 2, wherein the natural vegetable oil (D) comprises from 55 wt % to 90 wt % of oleic acid, relative to the total content of fatty acids in the natural vegetable oil (D).

### Claim 5 (depends on 2)

The composition according to claim 2, wherein the natural vegetable oil (D) is olive oil.

### Claim 6 (depends on 2)

The composition according to claim 2, wherein the biologically active substance (C) is at least one member selected from the group consisting of an amino acid, a vitamin, and a vitamin substance.

### Claim 7 (depends on 1)

The composition according to claim 1, wherein the natural vegetable oil (D) is at least one member selected from the group consisting of soybean oil, palm oil, rape seed oil, canola oil, olive oil, almond oil, avocado oil, and safflower oil.

### Claim 8 (depends on 7)

The composition according to claim 7, wherein the natural vegetable oil (D) comprises from 60 wt % to 95 wt % of an unsaturated fatty acid, relative to the total content of fatty acids in the natural vegetable oil (D), having 18 carbon atoms.

### Claim 9 (depends on 7)

The composition according to claim 7, wherein the natural vegetable oil (D) comprises from 55 wt % to 90 wt % of oleic acid, relative to the total content of fatty acids in the natural vegetable oil (D).

### Claim 10 (depends on 7)

The composition according to claim 7, wherein the natural vegetable oil (D) is olive oil.

### Claim 11 (depends on 7)

The composition according to claim 7, wherein the biologically active substance (C) is at least one member selected from the group consisting of an amino acid, a vitamin, and a vitamin substance.

### Claim 12 (depends on 2)

The composition according to claim 2, wherein the natural vegetable oil (D) is at least one member selected from the group consisting of soybean oil, palm oil, rape seed oil, canola oil, olive oil, almond oil, avocado oil, and safflower oil.

### Claim 13 (depends on 1)

The composition according to claim 1, wherein the natural vegetable oil (D) comprises from 60 wt % to 95 wt % of an unsaturated fatty acid, relative to the total content of fatty acids in the natural vegetable oil (D), having 18 carbon atoms.

### Claim 14 (depends on 1)

The composition according to claim 1, wherein the natural vegetable oil (D) comprises from 55 wt % to 90 wt % of oleic acid, relative to the total content of fatty acids in the natural vegetable oil (D).

### Claim 15 (depends on 1)

The composition according to claim 1, wherein the natural vegetable oil (D) is olive oil.

### Claim 16 (depends on 1)

The composition according to claim 1, wherein the biologically active substance (C) is at least one member selected from the group consisting of an amino acid, a vitamin, and a vitamin substance.

### Claim 17 (depends on 1)

The composition according to claim 1, wherein the layer substantially free of the biologically active substance has a thickness of from 30 μm to 110 μm.
