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US 11,067,571 B2Granted
Surface functionalization
AssigneeEmulate, Inc.
InventorsDaniel Levner, S. Jordan Kerns, Jefferson Puerta
Life of this patent
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Abstract
This invention is in the field of surface modification. In particular, the invention relates to the surface modification of microfluidic devices to alter surface hydrophobicity characteristics.
Claims16
A method of functionalizing the surface of a microfluidic channel comprising the steps of:
- a) providing;
- i) an enclosed microfluidic channel comprising an unmodified surface;
- ii) a bifunctional crosslinker selected from the group consisting of ANB-NOS, Sulfo-SAND, SANPAH and Sulfo-SANPAH;
- iii) surface hydrophobicity modifying molecules selected from the group consisting of PEG, TRIS, poly vinyl alcohol, and PLA;
- b) exposing at least a portion of said unmodified surface to said bifunctional crosslinker;
- c) activating said crosslinker under first conditions to create a crosslinked;
- and
- d) exposing said crosslinked surface to said surface hydrophobicity modifying molecules under second conditions to create a functionalized surface.
5 more elements
Dependencies are inferred from the claim text.