Use of resistant potato starch as a prebiotic to modify microbiota
AssigneeMcPharma Biotech Inc.
InventorsDerek McLaren, Earl McLaren
Life of this patent
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Abstract
Consumption of resistant potato starch results in changes to the gut microbiome in elderly adults, resulting in a healthier gut microbiome profile. Furthermore, consumption of resistant potato starch stimulates an increase in Bifidobacterium abundance in all individuals and also reduces levels of E. coli and Shigella. Furthermore, consumption of MSPrebiotic® increased the relative ratio of butyrate in the elderly and significantly reduced the use of stool softeners in the elderly.
Claims19
A method of promoting a symbiotic or non-dysbiotic gut microbiome profile in an individual having a dysbiotic gut microbiome profile-comprising administering to said individual an effective amount of an unmodified RS type 2 potato starch preparation that is at least 60% resistant starch on a dosage regimen, said individual having a dvsbiotic gut microbiome profile that is characterized by:
- a loss of beneficial microbial organisms within the gut microbiome, outgrowth of pathogenic micro-organisms within the gut microbiome, and/or a loss of overall microbial diversity in the gut microbiome compared to the gut microbiome profile of a control individual or compared to the gut microbiome profile that the said individual had when younger.
Dependencies are inferred from the claim text.