Method of long-term preservation of chemical and biological species using sugar glasses
AssigneeMcMaster University
InventorsVincent Ho Yin Leung, Sana Jahanshahi- Anbuhi, Carlos Filipe, M. Monsur Ali
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Abstract
A method of preserving the one or more chemical and/or biological species in a polymer matrix comprising pullulan and trehalose is described. The method includes combining the one or more chemical and/or biological species, an aqueous pullulan and a trehalose solution and drying the resultant mixture to provide a solid polymeric matrix. A polymeric matrix comprising one or more chemical and/or biological species and its use, for example, on surfaces for food preparation, for food preservation and in biological preparations is also described.
Claims23
A polymer matrix comprising pullulan, trehalose, and one or more viruses, wherein the one or more viruses are incorporated within the polymer matrix and the polymer matrix preserves and/or stabilizes the one or more viruses, and wherein the matrix comprises about 10 wt % to about 50 wt % of pullulan and about 50 wt % to about 90 wt % of trehalose, based on the dry weight of the matrix.
A polymer matrix comprising pullulan, trehalose and a virus, wherein the virus is incorporated within the polymer matrix and the polymer matrix preserves and/or stabilizes the virus, and wherein the matrix comprises about 10 wt % to about 50 wt % of pullulan and about 50 wt % to about 90 wt % of trehalose, based on the dry weight of the matrix.
A method of preserving and/or stabilizing one or more viruses comprising:
- a. combining one or more viruses, pullulan, trehalose, and water to provide a mixture, and
- b. drying the mixture to form a polymer matrix which preserves and/or stabilizes the one or more viruses,
- wherein the matrix comprises about 10 wt % to about 50 wt % of pullulan and about 50 wt % to about 90 wt % of trehalose, based on the dry weight of the matrix.
Dependencies are inferred from the claim text.