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US 11,040,004 B2Granted
Otic gel formulations for treating otitis externa
AssigneeOtonomy, Inc.
InventorCarl Lebel
Life of this patent
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Abstract
Disclosed herein are methods for the treatment of otic diseases or conditions with antimicrobial agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
Claims17
A method of treating otitis externa or a sign or symptom thereof, comprising administering into an external ear canal of a subject in need thereof, an aqueous thermoreversible gel composition,
- wherein:
- the composition comprises about 6.0% by weight of micronized ciprofloxacin and 15-17% by weight of poloxamer 407,
- the dose volume of the composition administered to the subject comprises about 12 mg of micronized ciprofloxacin, and
- the dose volume of the thermoreversible gel composition administered to the subject is about 0.2 mL.
1 more element
Dependencies are inferred from the claim text.