# US 11,029,539 B2 · Polymers and nanogel materials and methods for making and using the same

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- Number: US 11,029,539 B2
- Document ID: US11029539B2
- Status: Granted
- Kind: B2
- Application number: 16/657,163
- Filed: 2019-10-18
- Published: 2020-02-13
- Granted: 2021-06-08
- Earliest claimed: 2012-05-25
- Assignees: Johnson & Johnson Vision Care, Inc.
- Applicants: Johnson & Johnson Vision Care, Inc.
- Inventors: Charles W. Scales; Kevin P. McCabe; Brent Matthew Healy
- Web page: https://patentgrep.com/patent/US11029539B2

## CPC

- G02C 7/049: {Contact lenses having special fitting or structural features achieved by special materials or material structures}
- G02B 1/043: {Contact lenses}
- G02C 2202/16: Laminated or compound lenses
- G02C: SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES (trial frames for testing the eyes A61B3/04; goggles or eyeshields not having the same features as spectacles A61F9/00)
- G02B: OPTICAL ELEMENTS, SYSTEMS OR APPARATUS

## Abstract

Provided are articles such as medical devices which comprise at least one water soluble, crosslinked copolymer. The primary polymer chains of the copolymer are hydrophilic and independently have a degree of polymerization in the range of about 10 to about 10,000. The water soluble, crosslinked copolymers of the present invention are free from terminal substrate associating segments. The copolymers may be incorporated into a formulation from which the article is made or may be contacted with the article post-formation.

## Claims

### Claim 1

An ophthalmic device comprising a silicone-containing polymer and at least one water soluble, cross-linked copolymer comprising a plurality of primary polymer chains each having a degree of polymerization in the range of about 10 to about 10,000, wherein said copolymer is associated with at least one surface of said ophthalmic device and provides said ophthalmic device with a reduction in lipid uptake compared to the silicone-containing polymer of at least about 20%, and wherein said copolymer is free from terminal silicone segments.

### Claim 2 (depends on 1)

The ophthalmic device of claim 1 wherein said lipid uptake is less than about 12 μg/lens.

### Claim 3 (depends on 1)

The ophthalmic device of claim 1 wherein said lipid uptake is about 10 μg/lens or less.

### Claim 4 (depends on 1)

The ophthalmic device of claim 1 wherein said copolymer has a cross-linker to primary polymer chain molar ratio in the range of about 0.01 to about 3.

### Claim 5 (depends on 1)

The ophthalmic device of claim 1 wherein said primary polymer chains independently have a degree of polymerization in the range of about 50 to about 5,000.

### Claim 6 (depends on 1)

The ophthalmic device of claim 1 wherein said primary polymer chains independently have a degree of polymerization in the range of about 100 to about 1000.

### Claim 7 (depends on 1)

The ophthalmic device of claim 1 wherein the silicone-containing polymer contains one or more units derived from N-vinyl pyrrolidone.