# US 11,029,382 B2 · Echo sharing in imaging sequences with multiple delays and multiple spin echoes

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- Number: US 11,029,382 B2
- Document ID: US11029382B2
- Status: Granted
- Kind: B2
- Application number: 16/750,118
- Filed: 2020-01-23
- Published: 2020-07-23
- Granted: 2021-06-08
- Earliest claimed: 2019-01-23
- Assignees: Siemens Healthcare GmbH
- Applicants: Siemens Healthcare GmbH
- Inventors: Flavio Carinci; Dominik Paul; Mario Zeller
- Web page: https://patentgrep.com/patent/US11029382B2

## CPC

- G01R 33/5615: {Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]}
- G01R 33/5617: {using RF refocusing, e.g. RARE}
- G01R 33/482: {using a Cartesian trajectory}
- G01R 33/5602: {by filtering or weighting based on different relaxation times within the sample, e.g. T1 weighting using an inversion pulse}
- G01R 33/5608: {Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels (image data processing or generation, in general G06T)}
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)

## Abstract

Techniques are described for generating an MR image of an object using a multi spin-echo based imaging sequence with a plurality of k space segments using a preparation pulse. The technique included acquiring a first k-space dataset of the object using a first echo time and a first delay after the preparation pulse before the several spin-echoes are acquired. The technique further includes acquiring a second k space dataset of the object using a second echo time and a second delay after the preparation pulse, with at least one of the second echo time and the second delay time being different from the corresponding first echo time and the first delay time, generating a combined k space, and generating the MR image based on the combined k space dataset.

## Claims

### Claim 1

A method for generating a magnetic resonance (MR) image of an object using a multi spin-echo based imaging sequence in which, after one excitation RF pulse, several spin-echoes are acquired in a plurality of k space segments, and a preparation pulse is used before acquiring the several spin-echoes, the method comprising:
acquiring a first k-space dataset of the object using a first echo time and a first delay time after the preparation pulse and before the several spin-echoes are acquired, the first k space dataset comprising a first segment that is located closer to a k space center than a second segment, with a density of acquired k space data lines being smaller in the second segment than in the first segment;
acquiring a second k space dataset of the object using a second echo time and a second delay time after the preparation pulse, the at least one of the second echo time and the second delay time being different than the corresponding first echo time and the first delay time, the second k space dataset comprising a first segment that is located closer to a k space center than a second segment, with a density of acquired k space data lines being smaller in the second segment than in the first segment, and the acquired k space data lines in the second segment of the second k space dataset being different than the acquired k space data lines of the second segment of the first k space data set;
generating a combined k space dataset comprising a combined second segment in which k space data lines of the second segment of first k space dataset and k space data lines of the second segment of the second k space dataset are combined; and
generating an MR image based on the combined k space dataset.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the combined k space dataset comprises at least the first segment from the first or second k space dataset and the combined second segment.

### Claim 3 (depends on 1)

The method according to claim 1, wherein a density of the combined k space dataset is homogenous and constant over the combined k space dataset.

### Claim 4 (depends on 1)

The method according to claim 1, wherein the second segment in the first and second k space datasets is larger than the first segment in the first and second k space datasets, and each of the segments of the first and second k space datasets comprise the same number of acquired k space lines.

### Claim 5 (depends on 4)

The method according to claim 4, wherein in the second segments of the first and second k space datasets every nth k space data line is acquired,
wherein is an integer greater than or equal to 2, and
wherein a size of the second segments of the first and second k space datasets are increased by a factor n compared to the first segment where all k space data lines are acquired.

### Claim 6 (depends on 1)

The method according to claim 1, wherein:
the first segments of the first and second k space datasets each comprise the k space center and the highest density of acquired k space lines,
the first and second datasets each comprise a third segment located further away from the k space center than the second segment,
the further away from the k space center a corresponding segment is located, the lower the k space density of acquired k space lines, and
a combined k space dataset is generated additionally comprising a combined third segment in which the k space data lines of the third segment of the first k space dataset are combined with the k space data lines the third segment from the second k space dataset.

### Claim 7 (depends on 6)

The method according to claim 6, wherein:
a third k space dataset is acquired using a third echo time and a third delay after the preparation pulse, the third k space dataset comprising at least the first, second, and third segment,
at least one of the third echo time and the third delay time is different than the echo times and the delay times used for the first and second k space dataset,
the third segments of each of the k space data sets are acquired such that different k space lines are acquired in each of the third segments, and
the combined k space dataset comprises a combined third segment comprising k space lines from at least two different third segments from at least two different k space datasets.

### Claim 8 (depends on 1)

The method according to claim 1, wherein a number of segments corresponds to a number of spin-echoes acquired after a single excitation pulse.

### Claim 9 (depends on 1)

The method according to claim 1, wherein k space datasets with at least two different echo times and at least four different delay times are acquired.

### Claim 10

A magnetic resonance (MR) imaging system, comprising:
an MR system controller configured to:
generate an MR image of an object and to apply a multi spin-echo based imaging sequence in which, after one excitation RF pulse, several spin-echoes are acquired in a plurality of k space segments, and a preparation pulse is used before acquiring the several spin-echoes;
acquire a first k-space dataset of the object using a first echo time and a first delay after the preparation pulse and before the several spin-echoes are acquired, the first k space dataset comprising a first segment that is located closer to a k space center than a second segment, with a density of acquired k space data lines being smaller in the second segment than in the first segment,
acquire a second k space dataset of the object using a second echo time and a second delay after the preparation pulse, the at least one of the second echo time and the second delay time being different than the corresponding first echo time and the first delay time, the second k space dataset comprising a first segment that is located closer to a k space center than a second segment, with a density of acquired k space data lines being smaller in the second segment than in the first segment, and the acquired k space data lines in the second segment of the second k space dataset being different than the acquired k space data lines of the second segment of the first k space data set; and
generate a combined k space dataset comprising a combined second segment in which k space data lines of the second segment of first k space dataset and k space data lines of the second segment of the second k space dataset are combined; and
one or more processors configured to generate an MR image based on the combined k space dataset.

### Claim 11

A non-transitory computer-readable medium associated with a magnetic resonance imaging system having instructions stored thereon that, when executed by one or more processors of the magnetic resonance imaging system, cause the magnetic resonance imaging system to:
generate an MR image of an object and to apply a multi spin-echo based imaging sequence in which, after one excitation RF pulse, several spin-echoes are acquired in a plurality of k space segments, and a preparation pulse is used before acquiring the several spin-echoes;
acquire a first k-space dataset of the object using a first echo time and a first delay after the preparation pulse and before the several spin-echoes are acquired, the first k space dataset comprising a first segment that is located closer to a k space center than a second segment, with a density of acquired k space data lines being smaller in the second segment than in the first segment,
acquire a second k space dataset of the object using a second echo time and a second delay after the preparation pulse, the at least one of the second echo time and the second delay time being different than the corresponding first echo time and the first delay time, the second k space dataset comprising a first segment that is located closer to a k space center than a second segment, with a density of acquired k space data lines being smaller in the second segment than in the first segment, and the acquired k space data lines in the second segment of the second k space dataset being different than the acquired k space data lines of the second segment of the first k space data set; and
generate a combined k space dataset comprising a combined second segment in which k space data lines of the second segment of first k space dataset and k space data lines of the second segment of the second k space dataset are combined; and
generate an MR image based on the combined k space dataset.