# US 11,029,189 B2 · Liquid surface detecting apparatus and liquid surface detecting method using reflected light

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- Number: US 11,029,189 B2
- Document ID: US11029189B2
- Status: Granted
- Kind: B2
- Application number: 16/226,757
- Filed: 2018-12-20
- Published: 2019-06-27
- Granted: 2021-06-08
- Earliest claimed: 2017-12-26
- Assignees: Sysmex Corporation; Kawasaki Jukogyo Kabushiki Kaisha
- Applicants: Kawasaki Jukogyo Kabushiki Kaisha; Sysmex Corporation
- Inventors: Yukio Iwasaki; Satoshi Ouchi; Eiji Mitsui; Junichi Matsuoka; Takehiro Hasegawa
- Web page: https://patentgrep.com/patent/US11029189B2

## CPC

- G01F 23/292: Light {, e.g. infrared or ultraviolet}
- G01N 35/00584: {Control arrangements for automatic analysers}
- G01N 35/1009: {Characterised by arrangements for controlling the aspiration or dispense of liquids}
- G06T 7/0006: {using a design-rule based approach}
- G06T 7/62: of area, perimeter, diameter or volume
- G01N 2035/1025: {Fluid level sensing}
- G06T 2207/30004: Biomedical image processing
- G01F: MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL

## Abstract

A liquid surface detecting apparatus including: a retaining section that retains liquid as sample or reagent; a light emitter that emits light toward the liquid retained in the retaining section; an image capturing device that captures an image of the liquid retained in the retaining section; and a detecting device that detects a level of a liquid surface of the liquid retained in the retaining section based on the image of the liquid captured by the image capturing device, wherein the image capturing device is provided at a position such that the light, emitted by the light emitter and reflected by the liquid surface of the liquid, directly enters the image capturing device.

## Claims

### Claim 1

A liquid surface detecting apparatus comprising:
an aspirator configured to aspirate a liquid through a pipette, the liquid comprising a sample or reagent;
a light emitter that emits light toward the liquid in the pipette
an image capturing device that captures an image of the liquid in the pipette; and
a detecting device that detects a level of a liquid surface of the liquid in the pipette based on the image of the liquid captured by the image capturing device.

### Claim 2 (depends on 1)

The liquid surface detecting apparatus according to claim 1, wherein
the image capturing device is provided on an optical axis of the light emitted by the light emitter and specularly reflected by the liquid surface of the liquid.

### Claim 3 (depends on 1)

The liquid surface detecting apparatus according to claim 1, further comprising:
a determination device that determines whether or not an appropriate amount of liquid is retained in the pipette based on the level of the liquid surface of the liquid detected by the detecting device.

### Claim 4 (depends on 1)

The liquid surface detecting apparatus according to claim 1, wherein
the light emitter and the image capturing device are provided on the same side with respect to the pipette.

### Claim 5 (depends on 4)

The liquid surface detecting apparatus according to claim 4, wherein
the image capturing device is provided at a position such that the light, emitted by the light emitter and reflected by a curved portion of the liquid surface of the liquid, directly enters the image capturing device.

### Claim 6 (depends on 4)

The liquid surface detecting apparatus according to claim 4, further comprising:
a light shielding member that is provided on an opposite side with respect to the pipette from the light emitter and the image capturing device and that shields light, among the light emitted by the light emitter toward the liquid, which enters the image capturing device after being reflected at a position other than the liquid surface of the liquid.

### Claim 7 (depends on 1)

The liquid surface detecting apparatus according to claim 1, wherein
the image capturing device is capable of capturing an image of volumes of liquid retained in the retained sections at one time, and
the light emitter includes light emitting elements in a direction of arrangement of the volumes of liquid when the image capturing device captures the image of the volumes of liquid.

### Claim 8 (depends on 1)

The liquid surface detecting apparatus according to claim 1, further comprising:
a storing section with the liquid stored therein.

### Claim 9 (depends on 1)

The liquid surface detecting apparatus according to claim 1, wherein
the pipette is included in a hand section of a robot.

### Claim 10

A method of detecting a liquid surface, comprising:
aspirating a liquid through a pipette, the liquid comprising a sample or reagent;
emitting light toward the liquid in the pipette;
capturing an image of the liquid at a position such that the light, emitted in the light emission and reflected by a liquid surface of the liquid, directly enters the image capturing device; and
detecting a level of the liquid surface of the liquid based on the image of the liquid captured in the image capturing.