Methods and compositions to inhibit metastasis and to treat fibrosis and to enhance wound healing

A double-stranded nucleic acid molecule targeting a sequence selected from the group consisting of:

• SEQ ID NO:
• 1, SEQ ID NO:
• 2, SEQ ID NO:
• 3, and SEQ ID NO:
• 4, wherein the double-stranded nucleic acid comprises a single strand from 19 to 56 nucleotides in length comprising a sequence selected from the group consisting of:
• (SEQ ID NO:
• 5)
• 5′-GGAAGUAAGCUCAGGAUCUCAGCAG-3;
• (SEQ ID NO:
• 6)
• 5′-GUCCUUCAUUCGAGUCCUAUAGUCGUC-3′;
• (SEQ ID NO:
• 7)
• 5′-CACAUGAUGCCUGCUAGUU-3′;
• and
• (SEQ ID NO:
• 8)
• 5′-GACACUUUCUUCAUGAGCA-3′,
• or a sequence fully complementary thereto.