# US 11,026,983 B2 · Bifidobacterium breve CBT BR3 strain for promotion of growth and nutraceutical composition for promotion of growth containing the same

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- Number: US 11,026,983 B2
- Document ID: US11026983B2
- Status: Granted
- Kind: B2
- Application number: 16/382,669
- Filed: 2019-04-12
- Published: 2019-10-03
- Granted: 2021-06-08
- Earliest claimed: 2015-05-21
- Assignees: Cell Biotech Co., Ltd.
- Applicants: Cell Biotech Co., Ltd.
- Inventors: Myung Jun Chung
- Web page: https://patentgrep.com/patent/US11026983B2

## CPC

- A61K 35/745: Bifidobacteria
- A23L 33/135: Bacteria or derivatives thereof, e.g. probiotics
- C12N 1/20: Bacteria; Culture media therefor
- C12N 1/205: Bacterial isolates
- C12R 2001/01: Bacteria or Actinomycetales {; using bacteria or Actinomycetales}
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- C12N: MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media C12Q1/00)
- C12R: INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS

## Abstract

The present invention relates to a novel Bifidobacterium strain having an excellent growth promoting effect, and a nutraceutical composition for promotion of growth, which contains the strain. The strain of the present invention has a beneficial effect of promoting growth by promoting the digestion of human milk oligosaccharides to enhance immunity together with physical strength.

## Claims

### Claim 1

A method for alleviating one or more conditions selected from the group consisting of growth retardation, development retardation, and low body weight in a subject selected from the group consisting of human neonates, infants, and growing children, comprising:
administering to the subject a nutraceutical composition that comprises:
an effective amount of Bifidobacterium breve CBT BR3 strain deposited under accession number KCTC 12201BP; and
an excipient or a carrier,
wherein said bacteria strain is lyophilized.

### Claim 2 (depends on 1)

The method according to claim 1, further comprising orally administering a prebiotic substance.

### Claim 3 (depends on 2)

The method according to claim 2, wherein said nutraceutical composition comprises the prebiotic substance.

### Claim 4 (depends on 2)

The method according to claim 2, wherein said nutraceutical composition further comprises at least one additives selected from the group consisting of a binder, a disintegrant, and a lubricant.

### Claim 5 (depends on 1)

The method according to claim 1,
wherein an active ingredient in said nutraceutical composition for alleviating the one or more conditions consists of:
Bifidobacterium breve CBT BR3 strain deposited under accession number KCTC 12201BP and
at least one selected from the group consisting of Bifidobacterium longum subsp. infantis CBT BT1 (KCTC 11859BP) and/or and Bifidobacterium bifidum CBT BF3 (KCTC 12199BP).