# US 11,026,837 B2 · Systems and methods for ocular laser surgery and therapeutic treatments

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- Number: US 11,026,837 B2
- Document ID: US11026837B2
- Status: Granted
- Kind: B2
- Application number: 15/942,513
- Filed: 2018-03-31
- Published: 2019-04-11
- Granted: 2021-06-08
- Earliest claimed: 2017-03-31
- Assignees: Ace Vision Group, Inc.
- Applicants: AnnMarie Hipsley
- Inventors: AnnMarie Hipsley
- Web page: https://patentgrep.com/patent/US11026837B2

## CPC

- A61F 9/00802: {for photoablation}
- A61F 9/0017: {implantable in, or in contact with, the eye, e.g. ocular inserts}
- A61F 9/008: using laser
- A61F 9/00825: {for photodisruption}
- A61F 9/00838: {Correction of presbyopia}
- A61B 18/203: {applying laser energy to the outside of the body}
- A61B 2018/00577: {Ablation}
- A61B 2018/00613: {Irreversible electroporation}
- A61B 2018/00642: {with feedback, i.e. closed loop control}
- A61B 2018/00785: {Reflected power}
- A61B 2018/00904: {Automatic detection of target tissue}
- A61B 2018/20355: {Special scanning path or conditions, e.g. spiral, raster or providing spot overlap}
- A61B 2018/20359: {by movable mirrors, e.g. galvanometric}
- A61F 2009/00846: {Eyetracking}
- A61F 2009/00851: {Optical coherence topography [OCT]}
- A61F 2009/00865: {Sclera}
- A61F 2009/00878: {Planning}
- A61F 2009/0088: {based on wavefront}
- A61F 2009/00882: {based on topography}
- A61F 2009/00895: {Presbyopia}
- A61F 2009/00897: {Scanning mechanisms or algorithms}
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

Systems, devices and methods are provided to deliver microporation medical treatments to improve biomechanics, wherein the system includes a laser for generating a beam of laser radiation on a treatment-axis not aligned with a patient's visual-axis, operable for use in subsurface ablative medical treatments to create an array pattern of micropores that improves biomechanics. The array pattern of micropores is at least one of a radial pattern, a spiral pattern, a phyllotactic pattern, or an asymmetric pattern.

## Claims

### Claim 1

A system for delivering microporation medical treatments to improve biomechanics, the system comprising:
a laser for generating a beam of laser radiation on a treatment-axis not aligned with a patient's visual-axis, operable for use in subsurface ablative medical treatments to create an array pattern of micropores that improves biomechanics;
a housing;
a controller within the housing, in communication with the laser and operable to control dosimetry of the beam of laser radiation in application to a target tissue;
a lens operable to focus the beam of laser radiation onto a target tissue;
an automated off-axis subsurface anatomy tracking, measuring, and avoidance system; and
wherein the array pattern of micropores is at least one of a radial pattern, a spiral pattern, a phyllotactic pattern, or an asymmetric pattern, and wherein the array pattern of micropores has a controlled asymmetry which is an at least partial rotational asymmetry about the center of the array pattern and extends to at least 51 percent of the micropores of the array pattern.

### Claim 2 (depends on 1)

The system of claim 1, wherein the array pattern of micropores is a spiral pattern of an Archimedean spiral, a Euler spiral, a Fermat's spiral, a hyperbolic spiral, a lituus, a logarithmic spiral, a Fibonacci spiral, a golden spiral, or combinations thereof.

### Claim 3 (depends on 1)

The system of claim 1, wherein the array pattern has a number of clockwise spirals and a number of counter-clock wise spirals.

### Claim 4 (depends on 3)

The system of claim 3, wherein the number of clockwise spirals and the number of counterclockwise spirals are Fibonacci numbers or multiples of Fibonacci numbers.

### Claim 5 (depends on 3)

The system of claim 3, wherein the number of clockwise spirals and the number of counterclockwise spirals are in a ratio that converges on the golden ratio.

### Claim 6 (depends on 1)

The system of claim 1, wherein the at least partial rotational asymmetry extends to at least 20 micropores of the array pattern.

### Claim 7 (depends on 1)

The system of claim 1, wherein the array pattern of micropores has a random asymmetry.

### Claim 8 (depends on 1)

The system of claim 1, wherein the array pattern of micropores has a random symmetry.

### Claim 9

A method of delivering microporation medical treatments to improve biomechanics comprising:
generating, by a laser, a treatment beam on a treatment-axis not aligned with a patient's visual-axis in a subsurface ablative medical treatment to create an array of micropores that improves biomechanics;
controlling, by a controller in electrical communication with the laser, dosimetry of the treatment beam in application to a target tissue;
focusing, by a lens, the treatment beam onto the target tissue;
monitoring, by an automated off-axis subsurface anatomy tracking, measuring, and avoidance system, an eye position for application of the treatment beam; and
wherein the array pattern of micropores is at least one of a radial pattern, a spiral pattern, a phyllotactic pattern, or an asymmetric pattern, and wherein the array pattern of micropores has a controlled asymmetry which is an at least partial rotational asymmetry about the center of the array pattern and extends to at least 51 percent of the micropores of the array pattern.

### Claim 10 (depends on 9)

The method of claim 9, wherein the array pattern of micropores is a spiral pattern of an Archimedean spiral, a Euler spiral, a Fermat's spiral, a hyperbolic spiral, a lituus, a logarithmic spiral, a Fibonacci spiral, a golden spiral, or combinations thereof.

### Claim 11 (depends on 9)

The method of claim 9, wherein the array pattern has a number of clockwise spirals and a number of counter-clock wise spirals.

### Claim 12 (depends on 11)

The method of claim 11, wherein the number of clockwise spirals and the number of counterclockwise spirals are Fibonacci numbers or multiples of Fibonacci numbers.

### Claim 13 (depends on 11)

The method of claim 11, wherein the number of clockwise spirals and the number of counterclockwise spirals are in a ratio that converges on the golden ratio.

### Claim 14 (depends on 9)

The method of claim 9, wherein the at least partial rotational asymmetry extends to at least 20 micropores of the array pattern.

### Claim 15 (depends on 9)

The method of claim 9, wherein the array pattern of micropores has a random asymmetry.