# US 11,026,661 B2 · Imaging apparatus for diagnosis and program > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,026,661 B2 - Document ID: US11026661B2 - Status: Granted - Kind: B2 - Application number: 14/873,638 - Filed: 2015-10-02 - Published: 2016-01-28 - Granted: 2021-06-08 - Earliest claimed: 2013-04-05 - Assignees: Terumo Kabushiki Kaisha - Applicants: Terumo Kabushiki Kaisha - Inventors: Isao Mori; Ema Itoh - Web page: https://patentgrep.com/patent/US11026661B2 ## CPC - A61B 8/5261: {combining images from different diagnostic modalities, e.g. ultrasound and X-ray} - A61B 5/0035: {adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography} - A61B 5/0066: {Optical coherence imaging} - A61B 5/0084: {for introduction into the body, e.g. by catheters (A61B5/1459 takes precedence)} - A61B 5/6876: {Blood vessel} - A61B 8/12: in body cavities or body tracts, e.g. by using catheters - A61B 8/14: Echotomography - A61B 8/4416: {related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions} - A61B 5/02007: {Evaluating blood vessel condition, e.g. elasticity, compliance} - A61B 8/5207: {involving processing of raw data to produce diagnostic data, e.g. for generating an image} - A61B 8/54: {Control of the diagnostic device} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract An imaging apparatus is disclosed for diagnosis generating a first tomographic image and a second tomographic image inside a lumen of a measurement subject body by using an ultrasound signal which is transmitted and received by a first transmitting and receiving unit and an optical signal which is transmitted and received by a second transmitting and receiving unit in a case where a transmitting and receiving unit in which the first transmitting and receiving unit performing transmission and reception of the ultrasound signal and the second transmitting and receiving unit performing transmission and reception of the optical signal are disposed moves in an axial direction while rotating in the lumen of the measurement subject body. ## Claims ### Claim 1 An imaging apparatus for diagnosis generating a first tomographic image and a second tomographic image inside a lumen of a measurement subject body, the apparatus comprising: a transmitter and receiver comprising a first transmitter and receiver and a second transmitter and receiver, the first transmitter and receiver configured to perform transmission and reception of an ultrasound signal when rotating in the lumen of the measurement subject body, and the second transmitter and receiver configured to perform transmission and reception of an optical signal when rotating in the lumen of the measurement body; and a processor configured to: receive an input by a user to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image, the first tomographic image generated using the ultrasound signal and the second tomographic image generated using the optical signal; and execute a gain correction for changing a gain with respect to an ultrasound line data generated based on the ultrasound signal received by the first transmitter and receiver at a time of generating the first tomographic image based on the ultrasound line data, in accordance with the input by the user to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image. ### Claim 2 (depends on 1) The imaging apparatus for diagnosis according to claim 1, wherein the processor is further configured to: receive an input by the user of a type of a liquid inserted into the lumen when the transmitter and receiver moves in the axial direction while rotating in the lumen of the measurement subject body where the input by the user is to generate both the first tomographic image and the second tomographic image; and execute the gain correction, which includes changing the gain in accordance with the type of the liquid. ### Claim 3 (depends on 2) The imaging apparatus for diagnosis according to claim 2, wherein the type of the liquid is classified in accordance with characteristics of attenuation of the ultrasound signal. ### Claim 4 (depends on 2) The imaging apparatus for diagnosis according to claim 2, wherein the lumen of the measurement subject body is a blood vessel, and wherein the imaging apparatus for diagnosis further comprises: a first detector configured to detect a position of the lumen of the blood vessel based on the optical signal received by the second transmitter and receiver where the input by the user is to generate both the first tomographic image and the second tomographic image; and wherein the processor is configured to change the gain for a region detected outside of the position of the lumen by the first detector. ### Claim 5 (depends on 4) The imaging apparatus for diagnosis according to claim 4, comprising: a second detector configured to detect a position of an outer surface of a sheath in which the transmitter and receiver is interpolated, based on the ultrasound signal received by the first transmitter and receiver; and wherein the processor is configured to: calculate a distance between the position of the lumen detected by the first detector and the position of the outer surface of the sheath detected by the second detector; and revise the gain in accordance with the distance calculated. ### Claim 6 (depends on 5) The imaging apparatus for diagnosis according to claim 5, wherein the processor is configured to: perform a revision to cause the gain to increase as the distance calculated increases. ### Claim 7 (depends on 2) The imaging apparatus for diagnosis according to claim 2, wherein the first tomographic image is an intra-vascular and ultrasound the second tomographic image is an optical coherence tomography; and the input by the user of the type of liquid being information on a flushing liquid, and wherein the input by the user to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image and the input of the user of the type of liquid is input by the user via an operation panel. ### Claim 8 (depends on 1) The imaging apparatus for diagnosis according to claim 1, wherein the lumen of the measurement subject body is a blood vessel; and wherein the imaging apparatus for diagnosis further comprises: a first detector configured to detect a position of the lumen of the blood vessel based on the optical signal received by the second transmitter and receiver where the input by the user is to generate both the first tomographic image and the second tomographic image, and wherein the gain correction changes the gain for a region detected outside of the position of the lumen by the first detector. ### Claim 9 (depends on 8) The imaging apparatus for diagnosis according to claim 8, comprising: a second detector configured to detect a position of an outer surface of a sheath in which the transmitter and receiver is interpolated, based on the ultrasound signal received by the first transmitter and receiver; and wherein the processor is configured to: calculate a distance between the position of the lumen detected by the first detector and the position of the outer surface of the sheath detected by the second detector; and revise the gain in accordance with the distance calculated. ### Claim 10 (depends on 9) The imaging apparatus for diagnosis according to claim 9, wherein the processor is configured to: perform a revision to cause the gain to increase as the distance calculated increases. ### Claim 11 (depends on 1) A non-transitory computer readable medium configured to store a program for causing the processor of the imaging apparatus for diagnosis according to claim 1 to: receive the input by the user to generate both the first tomographic image or to generate only the first tomographic image; and execute the gain correction for changing a gain with respect to an ultrasound line data generated based on the ultrasound signal received by the first transmitter and receiver at a time of generating the first tomographic image based on the ultrasound line data received, in accordance with the input by the user to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image. ### Claim 12 An imaging apparatus for diagnosis generating a first tomographic image and a second tomographic image inside a lumen of a measurement subject body, the apparatus comprising: a transmitter and receiver comprising a first transmitter and receiver and a second transmitter and receiver, the first transmitter and receiver configured to perform transmission and reception of an ultrasound signal when rotating in the lumen of the measurement subject body, and the second transmitter and receiver configured to perform transmission and reception of an optical signal when rotating in the lumen of the measurement body; and a processor configured to: receive an input by a user to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image, the first tomographic image generated using the ultrasound signal and the second tomographic image generated using the optical signal; and change a signal strength of the ultrasound signal transmitted by the first transmitter and receiver, in accordance with the input by the user to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image. ### Claim 13 (depends on 12) The imaging apparatus for diagnosis according to claim 12, wherein the lumen of the measurement subject body is a blood vessel. ### Claim 14 (depends on 13) The imaging apparatus for diagnosis according to claim 13, wherein the first tomographic image is an intra-vascular ultrasound and the second tomographic image is an optical coherence tomography; and the input by the user of the type of liquid being information on a flushing liquid, and wherein the input by the user to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image and the input of the type of liquid is input by the user via an operation panel. ### Claim 15 (depends on 12) A non-transitory computer readable medium configured to store a program for causing the processor of the imaging apparatus for diagnosis according to claim 12 to: receive the input by the user to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image; and change the signal strength of the ultrasound signal transmitted by the first transmitter and receiver, in accordance with the input by the user to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image. ### Claim 16 A method of controlling an imaging apparatus for diagnosis generating a first tomographic image and a second tomographic image inside a lumen of a measurement subject body by using an ultrasound signal which is transmitted and received by a first transmitter and receiver and an optical signal which is transmitted and received by a second transmitter and receiver in a case where a transmitter and receiver in which the first transmitter and receiver performing transmission and reception of the ultrasound signal and the second transmitter and receiver performing transmission and reception of the optical signal are disposed moves in an axial direction while rotating in the lumen of the measurement subject body, the method comprising: receiving an input by a user to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image, the first tomographic image generated using the ultrasound signal and the second tomographic image generated using the optical signal; and changing a gain with respect to an ultrasound line data generated based on the ultrasound signal received by the first transmitter and receiver at a time of generating the first tomographic image based on the ultrasound line data received by the first transmitter and receiver. ### Claim 17 (depends on 16) The method according to claim 16, comprising: receiving an input by the user of a type of a liquid inserted into the lumen when the transmitter and receiver moves in the axial direction while rotating in the lumen of the measurement subject body where the input by the user is to generate both the first tomographic image and the second tomographic image; and changing the gain in accordance with the type of the liquid. ### Claim 18 (depends on 17) The method according to claim 17, wherein the lumen of the measurement subject body is a blood vessel. ### Claim 19 (depends on 18) The method according to claim 18, comprising: detecting a position of the lumen of the blood vessel based on the optical signal received by the second transmitter and receiver where the input by the user is to generate both the first tomographic image and the second tomographic image, and changing the gain for a region detected outside of the position of the lumen.