# US 11,026,639 B2 · Device for visualizing an internal organ of a patient and associated visualization method

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- Number: US 11,026,639 B2
- Document ID: US11026639B2
- Status: Granted
- Kind: B2
- Application number: 16/466,550
- Filed: 2017-12-07
- Published: 2020-03-12
- Granted: 2021-06-08
- Earliest claimed: 2016-12-08
- Assignees: Koelis
- Applicants: Koelis
- Inventors: Antoine Leroy; Patrick Henri; Michael Baumann; Eric Gaudard; Johan Sarrazin
- Web page: https://patentgrep.com/patent/US11026639B2

## CPC

- A61B 5/4381: {Prostate evaluation or disorder diagnosis}
- A61B 5/743: {Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots}
- A61B 5/7221: {Determining signal validity, reliability or quality (preventing, reducing or removing noise induced by motion artefacts A61B5/7207; noise originating from a therapeutic or surgical apparatus A61B5/7217)}
- A61B 5/7425: {Displaying combinations of multiple images regardless of image source, e.g. displaying a reference anatomical image with a live image}
- A61B 5/748: {Selection of a region of interest, e.g. using a graphics tablet}
- G06T 7/0012: {Biomedical image inspection}
- G06T 11/10: Texturing; Colouring; Generation of textures or colours (retouching, inpainting or scratch removal G06T5/77)
- G06T 19/00: Manipulating three-dimensional [3D] models or images for computer graphics
- G06T 2207/10088: Magnetic resonance imaging [MRI]
- G06T 2207/10104: Positron emission tomography [PET]
- G06T 2207/20076: Probabilistic image processing
- G06T 2207/30081: Prostate
- G06T 2210/41: Medical
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL

## Abstract

The invention concerns a device for displaying an internal organ of a patient comprising a computer (2) and a screen (3) connected to the computer in order to display at least one image of the internal organ. According to the invention, the computer is arranged to determine, from at least one medical examination previously carried out on the internal organ, at least one confidence area (10) and/or at least one affected area (11), at least partially encompassing one or more portions (9) of the internal organ where samples have been taken and/or at least partially encompassing one or more areas previously identified as suspect during a medical imaging procedure, and to display, on the screen, the image of the internal organ supplemented with the confidence area and/or the affected area. The invention also concerns a corresponding display method.

## Claims

### Claim 1

A device for visualizing an internal organ of a patient, comprising a computer and a screen connected to the computer in order to display at least one image of the internal organ, wherein the computer is configured:
to determine, from at least one medical examination previously carried out on the internal organ, at least one confidence zone and/or at least one affected zone, at least partially encompassing one or more portions of the internal organ where samples have been taken and/or at least partially encompassing one or more zones previously identified as suspect during a medical imaging procedure, the determination being based on:
a statistical approach to the presence of healthy or diseased tissues around a portion of the internal organ where at least one sample has been taken and/or around a zone previously identified as suspect during the medical imaging procedure;
and/or on an analysis of the samples taken:
to display, on the screen, the image of the internal organ supplemented with the confidence zone and/or the affected zone.

### Claim 2 (depends on 1)

The device as claimed in claim 1, in which the computer is arranged to project a three-dimensional image of the internal organ on the screen.

### Claim 3 (depends on 1)

The device as claimed in claim 1, in which the computer is arranged to project two-dimensional sectional images of the internal organ.

### Claim 4 (depends on 1)

The device as claimed in claim 1, in which the computer is arranged to display, on the image of the internal organ, at least one portion of the internal organ that has been punctured during the sampling procedures.

### Claim 5 (depends on 4)

The device as claimed in claim 4, in which the confidence zone and/or affected zone completely encompasses said portion.

### Claim 6 (depends on 4)

The device as claimed in claim 4, in which the confidence zone and/or the affected zone is displayed on the screen with a color gradient depending on the distance from the associated sampled portion and/or on the criticality of the disease possibly detected in said portion.

### Claim 7 (depends on 1)

The device as claimed in claim 1, in which the confidence zone and the affected zone are not displayed in the same color.

### Claim 8 (depends on 1)

The device as claimed in claim 1, in which the computer is configured in such a way as to display, on the image of the internal organ, at least one zone of the internal organ that is to be preserved.

### Claim 9 (depends on 1)

The device as claimed in claim 1, in which the computer is additionally configured to partition the internal organ into different elements and to display, on the image of the internal organ, the partition formed by these different elements.

### Claim 10 (depends on 9)

The device as claimed in claim 9, in which the confidence zone and/or the affected zone is formed by one or more elements.

### Claim 11 (depends on 1)

The device as claimed in claim 1, in which the computer is configured in such a way as to display, on the image of the internal organ, at least one item of information associated with the confidence zone and/or the affected zone.

### Claim 12 (depends on 1)

The device as claimed in claim 1, in which the computer is configured to be able to display a diseased general part encompassing at least some of the various affected zones.

### Claim 13 (depends on 1)

The device as claimed in claim 1, in which the computer is configured in such a way as to partition the internal organ into different elements and to display, on the image of the internal organ, the partition formed by these various elements, the computer additionally being configured in such a way as to display a diseased general part encompassing at least one element of the partition comprising one or more affected zones.

### Claim 14 (depends on 13)

The device as claimed in claim 13, in which the computer is configured in such a way that the diseased general part also encompasses at least one element of the partition in contact with the element of the partition comprising one or more affected zones.

### Claim 15 (depends on 1)

The device as claimed in claim 1, in which the computer is configured to export the displayed image to an external peripheral.

### Claim 16 (depends on 1)

The device as claimed in claim 1, in which the computer is arranged to define the affected zone and/or confidence zone also with the aid of a measurement error of the apparatus that was involved in the medical examination performed beforehand on the internal organ.

### Claim 17 (depends on 1)

A method for visualizing an internal organ of a patient with the aid of a device according to claim 1, comprising the step of determining the one or more confidence zones and/or affected zones and of displaying said one or more zones.

### Claim 18

A device for visualizing an internal organ of a patient, comprising a computer and a screen connected to the computer in order to display at least one image of the internal organ, wherein the computer is configured:
to determine, from at least one medical examination previously carried out on the internal organ, at least one confidence zone and/or at least one affected zone, at least partially encompassing one or more portions of the internal organ where samples have been taken and/or at least partially encompassing one or more zones previously identified as suspect during a medical imaging procedure, the determination being based on:
a statistical approach to the presence of healthy or diseased tissues around a portion of the internal organ where at least one sample has been taken and/or around a zone previously identified as suspect during the medical imaging procedure;
and/or on an analysis of the samples taken:
to display, on the screen, the image of the internal organ supplemented with the confidence zone and/or the affected zone,
wherein the confidence zone and/or the affected zone is displayed on the screen with a color gradient depending on the distance from the associated sampled portion and/or on the criticality of the disease possibly detected in said portion.

### Claim 19

A device for visualizing an internal organ of a patient which allows the clinician to better estimate the appropriate treatment, comprising a computer and a screen connected to the computer in order to display at least one image of the internal organ, the computer configured:
to determine, from at least one medical examination previously carried out on the internal organ, at least one confidence zone and/or at least one affected zone, at least partially encompassing one or more portions of the internal organ where samples have been taken and/or at least partially encompassing one or more zones of the internal organ previously identified as suspect during a medical imaging procedure, the determination being based on a statistical approach to the presence of healthy or diseased tissues around a portion of the internal organ where at least one sample has been taken and/or around a zone of the internal organ previously identified as suspect during the medical imaging procedure;
and/or on an analysis of the samples taken to display, on the screen, the image of the internal organ supplemented with the confidence zone and/or the affected zone.

### Claim 20

A device for visualizing an internal organ of a patient which allows the clinician to better estimate the appropriate treatment, comprising a computer and a screen connected to the computer in order to display at least one image of the internal organ, the computer configured:
to determine, from at least one medical examination previously carried out on the internal organ, at least one confidence zone and/or at least one affected zone, at least partially encompassing one or more portions of the internal organ where samples have been taken and/or at least partially encompassing one or more zones of the internal organ previously identified as suspect during a medical imaging procedure, the determination being based on a statistical approach to the presence of healthy or diseased tissues around a portion of the internal organ where at least one sample has been taken and/or around a zone of the internal organ previously identified as suspect during the medical imaging procedure;
and/or on an analysis of the samples taken to display, on the screen, the image of the internal organ supplemented with the confidence zone and/or the affected zone;
wherein the device comprise at least one man-machine interface that permit to modify the dimensions of the confidence zone and/or the affected zone once the image has been displayed.
