# US 11,026,422 B2 · Acid/anionic antimicrobial and virucidal compositions and uses thereof

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- Number: US 11,026,422 B2
- Document ID: US11026422B2
- Status: Granted
- Kind: B2
- Application number: 16/142,798
- Filed: 2018-09-26
- Published: 2019-03-28
- Granted: 2021-06-08
- Earliest claimed: 2017-09-26
- Assignees: Ecolab USA Inc.
- Applicants: Ecolab USA Inc.
- Inventors: Catherine Hanson; Junzhong Li; David D. McSherry; Stacy Fawbush; Kaitlin Lake; Gerard Hinrichs; Joshua Luedtke; Richard Staub; Derrick Anderson
- Web page: https://patentgrep.com/patent/US11026422B2

## CPC

- A01N 37/36: containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N 25/30: characterised by the surfactants
- A01N 31/02: Acyclic compounds
- A01N 31/08: Oxygen or sulfur directly attached to an aromatic ring system
- A01N 47/28: Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< (isoureas, isothioureas A01N47/42)
- A61L 2/18: Liquid substances
- C11D 1/143: {Sulfonic acid esters}
- C11D 3/2086: {Hydroxy carboxylic acids-salts thereof}
- C11D 3/48: Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
- A61L 2/22: Phase substances, e.g. smokes or aerosols
- A61L 2103/15: Laboratory, medical or dentistry appliances, e.g. catheters or sharps
- A61L 2202/14: Means for controlling sterilisation processes, data processing, presentation and storage means, e.g. sensors, controllers, programs
- C11D 2111/14: Hard surfaces
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- C11D: DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL

## Abstract

Antimicrobial compositions including at least one acid and at least one anionic surfactant are provided. In particular, food contact antimicrobial compositions including at least one acid and at least one anionic surfactant provide a no-rinse compositions efficacious against Norovirus, having acceptable use solution pH that do not require use of personal protective equipment (PPE), are surface compatible and do not leave residues on treated surfaces are provided. Methods of cleaning a surface with the compositions are also provided.

## Claims

### Claim 1

A liquid virucidal composition consisting of:
from about 20 wt-% to about 40 wt-% of at least one weak acid consisting of lactic acid, citric acid, and/or malic acid;
from about 5 wt-% to about 15 wt-% of at least one strong acid consisting of methane sulfonic acid, phosphoric acid, sulfuric acid, and/or sodium bisulfate;
from about 5 wt-% to about 20 wt-% of at least one sulfonate, sulfate and/or carboxylate anionic surfactant;
water; and
optionally at least one additional functional ingredient including nonionic surfactant, solidifying agents, fragrances, and/or dyes,
wherein the composition is a liquid concentrate having an acidic pH that is non-flammable;
wherein a use pH of the composition is from about 1.5 to about 4; and
wherein the composition is a no-rinse virucidal composition effective against Norovirus.

### Claim 2 (depends on 1)

The composition of claim 1, wherein the anionic surfactant is a C8-C22 alkyl sulfonate, and/or alpha sulfonated carboxylic acid or its ester.

### Claim 3 (depends on 2)

The composition of claim 2, wherein the C8-C22 alkyl sulfonate is linear alkyl benzene sulfonic acid.

### Claim 4 (depends on 1)

The composition of claim 1, further comprising the nonionic surfactant, wherein the nonionic surfactant is an alkoxylated nonionic surfactant having an ethylene oxide/propylene oxide (EO/PO) block copolymer.

### Claim 5 (depends on 1)

The composition of claim 1, wherein the composition has a use pH from about 2 to about 4.

### Claim 6 (depends on 1)

The composition of claim 1, wherein the composition further comprises the at least one additional functional ingredient from about 1 wt-% to about 38 wt %.

### Claim 7 (depends on 1)

The composition of claim 1, wherein the at least one weak acid comprises from about 20 wt-% to about 38 wt-% of the composition and the at least one strong acid comprises from about 5 wt-% to about 10 wt-% of the composition.

### Claim 8 (depends on 1)

The composition of claim 1, wherein the liquid is saturated onto a wipe substrate.

### Claim 9 (depends on 1)

The composition of claim 1, wherein the liquid is provided as a ready to use concentration comprising from about 5 ppm to about 10,000 ppm of the at least one weak acid and the at least one strong acid, and from about 10 ppm to about 6,000 ppm of the anionic surfactant.

### Claim 10 (depends on 1)

A method of using a virucidal composition, comprising:
contacting the virucidal composition of claim 1 to a surface in need of treatment,
wherein the method does not require a rinse step and the contacting provides antiviral inactivation efficacy against Norovirus of at least a 3-log reduction to complete inactivation.

### Claim 11 (depends on 10)

The method of claim 10, wherein the contacting is by wiping, dipping, immersing, or spraying, and wherein the surface is a hard surface, a precleaned hard surface, a surface contaminated with Norovirus and/or biofilm, and/or a human or mammalian tissue.

### Claim 12 (depends on 10)

The method of claim 10, wherein the contacting provides complete kill of the Norovirus in less than 1 minute, and wherein the contacting step is at an aqueous use temperature from about 40° F.-160° F.

### Claim 13 (depends on 10)

The method of claim 10, wherein the concentrate is diluted at a rate of from about ⅛ oz./gal. to about 2 oz./gal. to form a use solution comprising from about 5 ppm to about 10,000 ppm of at least one acid, and from about 10 ppm to about 6000 ppm of at least one anionic surfactant.

### Claim 14 (depends on 10)

The method of claim 10, wherein a sensor and/or indicator is employed to measure and detect at least one of the following: solution pH at which the compositions loses biocidal efficacy, concentration of anionic surfactant in the use solution, fluorescence, and/or conductivity.

### Claim 15

A liquid virucidal composition consisting of:
from about 150 ppm to about 700 ppm of at least one strong acid consisting of methane sulfonic acid, phosphoric acid, sulfuric acid, and/or sodium bisulfate and from about 1500 ppm to about 4000 ppm of at least one weak acid consisting of lactic acid, citric acid, and/or malic acid;
from about 400 ppm to about 700 ppm of at least one sulfonate, sulfate and/or carboxylate anionic surfactant;
water; and
optionally at least one additional functional ingredient including nonionic surfactant, solidifying agents, fragrances, and/or dyes,
wherein the composition is non-flammable;
wherein the pH of the composition is from about 1.5 to about 4; and
wherein the composition is a no-rinse viricidal composition effective against Norovirus.

### Claim 16 (depends on 15)

The composition of claim 15, wherein the anionic surfactant is a C8-C22 alkyl sulfonate and/or alpha sulfonated carboxylic acid or its ester.

### Claim 17 (depends on 15)

The composition of claim 15, wherein the at least one additional functional ingredient is the nonionic surfactant.

### Claim 18 (depends on 15)

A method of inactivating a virus, said method comprising:
contacting the virucidal composition of claim 15 to a surface in need of treatment;
wherein the contacting provides antiviral inactivation efficacy against Norovirus of at least a 3 log reduction to complete inactivation within less 1 minute, or preferably less than 30 seconds, and
wherein the method does not require a rinse step and does not impart a residue on the treated surface.

### Claim 19 (depends on 18)

The method of claim 18, wherein the method further provides efficacy against a small, non-enveloped virus, a large, non-enveloped virus, and/or an enveloped virus.