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US 11,020,515 B2Granted
Method for inhibiting platelet interaction with biomaterial surfaces
AssigneeMedtronic ATS Medical, Inc.
InventorBrian Pederson
Life of this patent
Estimating the term…
Abstract
A method for passivating a biomaterial surface includes modifying proteinaceous material disposed at the biomaterial surface. The passivation may be effectuated by exposing the biomaterial surface to therapeutic electrical energy in the presence of blood or plasma.
Claims20
A medical device comprising:
- a biomaterial surface;
- and
- a layer of proteinaceous material adhered to the biomaterial surface, the proteinaceous material including at least one of conformationally altered fibrinogen and albumin, the proteinaceous material configured to exhibit at least one anti-thrombogenic property at the biomaterial surface following placement of the biomaterial surface within a human body, wherein the biomaterial surface is exposed to an electrical energy in the presence of a proteinaceous fluid to cause proteinaceous material to adhere to the biomaterial surface prior to placement of the biomaterial surface within the human body.
A medical device comprising:
- a biomaterial surface;
- and
- a layer of proteinaceous material adhered to the biomaterial surface, the proteinaceous material including at least one of conformationally altered fibrinogen and albumin, the proteinaceous material configured to exhibit at least one anti-thrombogenic property at the biomaterial surface following placement of the biomaterial surface within a human body, wherein the biomaterial surface is exposed to a treated proteinaceous fluid prior to placement of the biomaterial surface within the human body, wherein treatment of the proteinaceous fluid comprises exposing the proteinaceous fluid to an electrical energy.
Dependencies are inferred from the claim text.