Compounds supports hematopoietic stem cells and red blood cells
AssigneeBoard of Regents, The University of Texas System
InventorsChengcheng Zhang, Yi Liu, Junke Zheng, Mi Deng, Chuo Chen, Jiawei Liu
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Abstract
The present disclosure relates to methods of using a compound to induce regeneration of hematopoietic stem cells or increase the recovery of red blood cells. In some aspects, the present methods can be used to with or in place of erythropoietin in patients to mitigate the side effects of erythropoietin.
Claims10
A method of promoting regeneration of hematopoietic stern cells in a patient in need of regeneration of hematopoietic stem cells comprising administering to the patient a pharmaceutically effective amount of a compound in a substantially isolated or purified form and has the formula:
- wherein carbon 1 is in the R configuration, S configuration, or a mixture thereof;
- or a pharmaceutically acceptable salt or optical isomer thereof, wherein the compound is not comprised in a toad skin extract.
Dependencies are inferred from the claim text.