A method for inhibiting in an animal a parvovirus infection, an erythrovirus infection, or a parvovirus B19 infection, comprising one or more administrations of one or more compositions comprising an mVLP comprising a polypeptide,
- wherein
- the compositions may be the same or different if there is more than one administration,
- the polypeptide comprises a VP2 polypeptide with at least one amino acid modification relative to a wild type VP2,
- the wild type VP2 has the amino acid sequence of SEQ ID NO:
- 1,
- the at least one amino acid modification (1) comprises (a) Y401F and (b) Q399N or Q404T or (2) is Y401F, and
- the polypeptide is not construct J.