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US 11,001,625 B2Granted
VHH based binding antibodies for anthrax and botulinum toxins and methods of making and using therefor
AssigneeTufts University
InventorCharles B. Shoemaker
Life of this patent
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Abstract
Methods, compositions and kits are provided for treating a subject exposed to or at risk for exposure to a disease agent, methods, compositions and kits having a pharmaceutical composition including at least one recombinant binding protein or a source of expression of the binding protein, wherein the binding protein neutralizes at least one or a plurality of disease agents that are toxins, for example at least one of a Botulinum toxin or an Anthrax toxin.
Claims7
A recombinant binding protein that specifically binds to a Bacillus anthracis toxin, wherein the binding protein comprises an amino acid sequence selected from SEQ ID NO:
- 81, SEQ ID NO:
- 93, SEQ ID NO:
- 13, SEQ ID NO:
- 1, SEQ ID NO:
- 3, SEQ ID NO:
- 5, SEQ ID NO:
- 7, SEQ ID NO:
- 9, SEQ ID NO:
- 11, SEQ ID NO:
- 15, SEQ ID NO:
- 103, SEQ ID NO:
- 105, or a combination thereof.
9 more elements
Dependencies are inferred from the claim text.