SynP160, a promoter for the specific expression of genes in rod photoreceptors
AssigneeFriedrich Miescher Institute for Biomedical Research
InventorsDominik Hartl, Josephine Juettner, Arnaud Krebs, Botond Roska, Dirk Schuebeler
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Abstract
The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 300 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod photoreceptors of a gene when operatively linked to a nucleic acid sequence coding for said gene.
Claims17
An isolated nucleic acid sequence encoding a protein operably linked to a promoter of at least 300 base pairs having at least 80% identity to the nucleotide sequence of SEQ ID NO:
- 1, wherein the promoter is heterologous to the protein coding region and is capable of driving functional expression of the protein in rod photoreceptor cells.
Dependencies are inferred from the claim text.