Systems and methods of mitigating negative effects of therapies with transcutaneous vibration
AssigneeApollo Neuroscience, Inc.
InventorsDavid Mayer Lowell Rabin, Kathryn Fantauzzi
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Abstract
Systems and methods to mitigate negative effects of a drug in a treatment of a mental health condition include administering a drug to a subject in a therapy session; determining effects of the drug, the effects being counterproductive to the therapy session; and providing tactile stimulation to a subject with a stimulation device that generates transcutaneous vibratory output to be applied to a portion of a body of the subject during the therapy session, wherein the transcutaneous vibratory output is selected to reduce the counterproductive effects of the drug.
Claims32
A method to mitigate negative effects of a drug in a treatment of a mental health condition, the method comprising:
- administering the drug to a subject in a controlled therapy session;
- determining effects of the drug, the effects being counterproductive to the controlled therapy session;
- and
- providing tactile stimulation to the subject with a stimulation device that generates transcutaneous vibratory output to be applied to a portion of a body of the subject during the controlled therapy session,
- wherein the transcutaneous vibratory output is generated by a combination of oscillations, the combination of oscillations comprising a first oscillation at a first frequency and a second oscillation at a second frequency that together form an output with a first predetermined beat pattern,
- wherein the first predetermined beat pattern is selected to reduce the counterproductive effects of the drug,
- wherein the first predetermined beat pattern, in response to the effects being counterproductive, is adjusted from the first predetermined beat pattern to a second predetermined beat pattern over a time period in the controlled therapy session by adjusting at least one of the first frequency or the second frequency over the time period, and
- wherein the second predetermined beat pattern is selected to reduce the counterproductive effects of the drug.
A method to mitigate negative effects of a drug in a treatment of a mental health condition, the method comprising:
- administering the drug to a subject in a controlled therapy session;
- determining effects of the drug, the effects being counterproductive to the controlled therapy session;
- providing tactile stimulation to the subject with a stimulation device that generates transcutaneous vibratory output having a selected envelope and a selected base tone to be applied to a portion of a body of the subject during the controlled therapy session;
- and
- wherein the transcutaneous vibratory output is selected to reduce the counterproductive effects of the drug, and
- wherein the transcutaneous vibratory output has a first predetermined beat pattern and the first predetermined beat pattern, in response to the effects being counterproductive, is adjusted to a second predetermined beat pattern over a time period in the controlled therapy session.
A method of treating a subject comprising:
- administering a drug during a controlled therapy session;
- determining effects of the drug on the subject in the controlled therapy session, the effects being counterproductive to the controlled therapy session;
- with a simulation device, applying to a portion of a body of the subject a transcutaneous vibratory output having a perceived pitch and a perceived beat;
- and
- selectively altering the perceived pitch and the perceived beat to counteract counterproductive effects of the drug,
- wherein at least one of the perceived pitch or the perceived beat are adjusted from a first frequency to a second frequency over a time period in the controlled therapy session.
Dependencies are inferred from the claim text.