Compositions and methods for treating retinopathy
AssigneeMarshall University Research Corporation
InventorsZijian Xie, Joseph I. Shapiro
Life of this patent
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Abstract
Methods for treating retinopathy are provided and include administering an effective amount of a polypeptide antagovist of a Na/K ATPase/Src receptor complex to a subject. The retinopathy can include diabetic retinopathy. Methods of decreasing angiogenesis in a retinal vasculature are also provided and include the step of administering, such as by intravitreous injection, a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof.
Claims10
A method for treating retinopathy, comprising administering an effective amount of polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof, wherein the polypeptide antagonist comprises the sequence of SEQ ID NO:
- 1, or a fragment thereof.
A method of decreasing angiogenesis in a retinal vasculature, comprising administering a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof, wherein the polypeptide antagonist comprises the sequence of SEQ ID NO:
- 1, or a fragment thereof.
Dependencies are inferred from the claim text.