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AssigneeZora Biosciences Oy
InventorsReijo Laaksonen, Kim Ekroos, Reini Hurme, Riikka Katainen
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The present invention inter alia provides a method, and use thereof, of predicting severe CVD complications such as AMI or CVD death by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in predicting these CVD complications than currently utilized clinical markers. Also provided is an antibodies towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating CVD complications. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of CVD complications.
A method for determining whether a subject is at risk to develop one or more cardiovascular disease (CVD) complications, comprising:
A method for evaluating the effectiveness of a lipid modifying treatment of CVD and/or one or more of its complications, in a subject, comprising:
A method of choosing an appropriate lipid modifying treatment of CVD and/or one or more of its complications, in a subject, comprising:
A method of treating or preventing cardiovascular disease (CVD) complications in a subject, the method comprising:
A method for detecting a lipid concentration(s), a lipid-lipid concentration ratio(s) and/or a lipid-clinical concentration ratio(s) in a sample from a coronary artery disease subject, comprising:
A method for determining whether a subject is at risk to develop one or more cardiovascular disease (CVD) complications, comprising:
Dependencies are inferred from the claim text.