US 10,954,265 B2Granted

Structures and mechanism for the design of highly potent glucocorticoids

AssigneeVan Andel Research Institute

InventorsHuaqiang Eric Xu, Yuanzheng He

Life of this patent

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Abstract

The present invention relates to novel glucocorticoid compounds. The invention also relates to methods of using these compounds, the synthesis of these compounds, and to compositions and formulations comprising the glucocorticoid compounds, and uses thereof.

Claims10

Dependent claims

A compound selected from:

or a pharmaceutically acceptable salt thereof.

Dependencies are inferred from the claim text.

Facts

Application: 16/341,275Filed 13 Oct 2017 · us provisional application
Priority: 14 Oct 2016
Published: US 2019/0263853 A129 Aug 2019
Granted: 23 Mar 2021
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61P 5/44
Of the suprarenal hormones: glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
C07J 71/0047
Nitrogen only: at position 2
A61P 11/06
Drugs for disorders of the respiratory system: antiasthmatics
A61P 19/02
Drugs for skeletal disorders: for joint disorders, e.g. arthritis, arthrosis

Family

Application62/408,314Us provisional application · filed 14 Oct 2016
US 2019/0263853 A1Pre-grant publication · published 29 Aug 2019
US 10,954,265 B2This patent

From the US filing history. Foreign family members aren’t listed.

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