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AssigneeZoetis Services LLC
InventorsJacqueline Gayle Marx, John Morgan Hardham, Paul J. Dominowski, Vicki Jon Rapp Gabrielson, Monica Balasch Sanuy, Marta Cabana Sumsi, Laia Plaja Dilme, Alicia Urniza Hostench, Oscar Romero Galindo
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The present invention is directed to novel immunogenic compositions that protect swine from disease caused by porcine epidemic diarrhea virus (PEDV). The present invention is also directed to novel immunogenic compositions that protect swine from disease caused by porcine deltacoronavirus (PDCoV), alone or as combination vaccine to protect against PEDV. The compositions of the invention provide killed viruses whose effectiveness is enhanced by the selection of preferred adjuvants. Novel culture methods are also employed to increase reproducible yield of cultured viruses. Live vaccines are also provided from the Calaf14 PEDV isolate.
A method of immunizing a piglet against Porcine Epidemic Diarrhea virus (PEDV), the method comprising administering to said piglet an efficient amount of colostrum from a sow immunized with a vaccine comprising an inactivated PEDV adjuvanted with oil-in-water emulsion and aluminum hydroxide.
A method of immunizing a piglet against Porcine Deltacoronavirus virus (PDCoV), the method comprising administering to said piglet an efficient amount of colostrum from a sow immunized with a vaccine comprising an inactivated PDCoV adjuvanted with oil-in-water emulsion and aluminum hydroxide.
Dependencies are inferred from the claim text.